MIRAGE: Multimodal foundation model and benchmark for comprehensive retinal OCT image analysis

Fuente: arXiv
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Auteurs principaux: Morano, José, Fazekas, Botond, Sükei, Emese, Fecso, Ronald, Emre, Taha, Gumpinger, Markus, Faustmann, Georg, Oghbaie, Marzieh, Schmidt-Erfurth, Ursula, Bogunović, Hrvoje
Format: Preprint
Publié: 2025
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author Morano, José
Fazekas, Botond
Sükei, Emese
Fecso, Ronald
Emre, Taha
Gumpinger, Markus
Faustmann, Georg
Oghbaie, Marzieh
Schmidt-Erfurth, Ursula
Bogunović, Hrvoje
author_facet Morano, José
Fazekas, Botond
Sükei, Emese
Fecso, Ronald
Emre, Taha
Gumpinger, Markus
Faustmann, Georg
Oghbaie, Marzieh
Schmidt-Erfurth, Ursula
Bogunović, Hrvoje
contents Artificial intelligence (AI) has become a fundamental tool for assisting clinicians in analyzing ophthalmic images, such as optical coherence tomography (OCT). However, developing AI models often requires extensive annotation, and existing models tend to underperform on independent, unseen data. Foundation models (FMs), large AI models trained on vast unlabeled datasets, have shown promise in overcoming these challenges. Nonetheless, available FMs for ophthalmology lack extensive validation, especially for segmentation tasks, and focus on a single imaging modality. In this context, we propose MIRAGE, a novel multimodal FM for the analysis of OCT and scanning laser ophthalmoscopy (SLO) images. Additionally, we propose a new evaluation benchmark with OCT/SLO classification and segmentation tasks. The comparison with general and specialized FMs and segmentation methods shows the superiority of MIRAGE in both types of tasks, highlighting its suitability as a basis for the development of robust AI systems for retinal OCT image analysis. Both MIRAGE and the evaluation benchmark are publicly available: https://github.com/j-morano/MIRAGE.
format Preprint
id arxiv_https___arxiv_org_abs_2506_08900
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MIRAGE: Multimodal foundation model and benchmark for comprehensive retinal OCT image analysis
Morano, José
Fazekas, Botond
Sükei, Emese
Fecso, Ronald
Emre, Taha
Gumpinger, Markus
Faustmann, Georg
Oghbaie, Marzieh
Schmidt-Erfurth, Ursula
Bogunović, Hrvoje
Computer Vision and Pattern Recognition
Artificial intelligence (AI) has become a fundamental tool for assisting clinicians in analyzing ophthalmic images, such as optical coherence tomography (OCT). However, developing AI models often requires extensive annotation, and existing models tend to underperform on independent, unseen data. Foundation models (FMs), large AI models trained on vast unlabeled datasets, have shown promise in overcoming these challenges. Nonetheless, available FMs for ophthalmology lack extensive validation, especially for segmentation tasks, and focus on a single imaging modality. In this context, we propose MIRAGE, a novel multimodal FM for the analysis of OCT and scanning laser ophthalmoscopy (SLO) images. Additionally, we propose a new evaluation benchmark with OCT/SLO classification and segmentation tasks. The comparison with general and specialized FMs and segmentation methods shows the superiority of MIRAGE in both types of tasks, highlighting its suitability as a basis for the development of robust AI systems for retinal OCT image analysis. Both MIRAGE and the evaluation benchmark are publicly available: https://github.com/j-morano/MIRAGE.
title MIRAGE: Multimodal foundation model and benchmark for comprehensive retinal OCT image analysis
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2506.08900