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Main Authors: van der Schaar, Mihaela, Peck, Richard, McKinney, Eoin, Weatherall, Jim, Bailey, Stuart, Rochon, Justine, Anagnostopoulos, Chris, Marquet, Pierre, Wood, Anthony, Best, Nicky, Amad, Harry, Piskorz, Julianna, Kacprzyk, Krzysztof, Salama, Rafik, Gunther, Christina, Frau, Francesca, Pugeat, Antoine, Hernandez, Ramon
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2506.09102
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author van der Schaar, Mihaela
Peck, Richard
McKinney, Eoin
Weatherall, Jim
Bailey, Stuart
Rochon, Justine
Anagnostopoulos, Chris
Marquet, Pierre
Wood, Anthony
Best, Nicky
Amad, Harry
Piskorz, Julianna
Kacprzyk, Krzysztof
Salama, Rafik
Gunther, Christina
Frau, Francesca
Pugeat, Antoine
Hernandez, Ramon
author_facet van der Schaar, Mihaela
Peck, Richard
McKinney, Eoin
Weatherall, Jim
Bailey, Stuart
Rochon, Justine
Anagnostopoulos, Chris
Marquet, Pierre
Wood, Anthony
Best, Nicky
Amad, Harry
Piskorz, Julianna
Kacprzyk, Krzysztof
Salama, Rafik
Gunther, Christina
Frau, Francesca
Pugeat, Antoine
Hernandez, Ramon
contents This manifesto represents a collaborative vision forged by leaders in pharmaceuticals, consulting firms, clinical research, and AI. It outlines a roadmap for two AI technologies - causal inference and digital twins - to transform clinical trials, delivering faster, safer, and more personalized outcomes for patients. By focusing on actionable integration within existing regulatory frameworks, we propose a way forward to revolutionize clinical research and redefine the gold standard for clinical trials using AI.
format Preprint
id arxiv_https___arxiv_org_abs_2506_09102
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Revolutionizing Clinical Trials: A Manifesto for AI-Driven Transformation
van der Schaar, Mihaela
Peck, Richard
McKinney, Eoin
Weatherall, Jim
Bailey, Stuart
Rochon, Justine
Anagnostopoulos, Chris
Marquet, Pierre
Wood, Anthony
Best, Nicky
Amad, Harry
Piskorz, Julianna
Kacprzyk, Krzysztof
Salama, Rafik
Gunther, Christina
Frau, Francesca
Pugeat, Antoine
Hernandez, Ramon
Computers and Society
Artificial Intelligence
This manifesto represents a collaborative vision forged by leaders in pharmaceuticals, consulting firms, clinical research, and AI. It outlines a roadmap for two AI technologies - causal inference and digital twins - to transform clinical trials, delivering faster, safer, and more personalized outcomes for patients. By focusing on actionable integration within existing regulatory frameworks, we propose a way forward to revolutionize clinical research and redefine the gold standard for clinical trials using AI.
title Revolutionizing Clinical Trials: A Manifesto for AI-Driven Transformation
topic Computers and Society
Artificial Intelligence
url https://arxiv.org/abs/2506.09102