Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Preprint |
| Published: |
2025
|
| Subjects: | |
| Online Access: | https://arxiv.org/abs/2506.09708 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1866915338753409024 |
|---|---|
| author | Guglietta, Fabio Scarpolini, Martino Andrea Viola, Francesco Biferale, Luca |
| author_facet | Guglietta, Fabio Scarpolini, Martino Andrea Viola, Francesco Biferale, Luca |
| contents | We present a Lagrangian analysis of turbulent blood flow in the human left heart using high-fidelity simulations based on a patient-specific anatomical model. Leveraging a fully coupled fluid-structure-electrophysiology interaction (FSEI) framework, we track the motion of Lagrangian (passive) tracers to investigate the multiscale statistical properties of velocity fluctuations over more than four decades. Our analysis reveals strong Lagrangian intermittency throughout the left heart, reflecting the complex and unsteady nature of cardiovascular flow. The present work underscores the sensitivity of Lagrangian statistics to physiological parameters and highlights their potential for improving the understanding of pathological flow conditions in cardiovascular systems. Such Lagrangian tool provides a statistical foundation for modeling shear-induced damage in red blood cells (hemolysis), with implications for the evaluation of prosthetic valves and blood-contacting medical devices. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2506_09708 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Lagrangian analysis of turbulent blood flow in the human left heart Guglietta, Fabio Scarpolini, Martino Andrea Viola, Francesco Biferale, Luca Fluid Dynamics We present a Lagrangian analysis of turbulent blood flow in the human left heart using high-fidelity simulations based on a patient-specific anatomical model. Leveraging a fully coupled fluid-structure-electrophysiology interaction (FSEI) framework, we track the motion of Lagrangian (passive) tracers to investigate the multiscale statistical properties of velocity fluctuations over more than four decades. Our analysis reveals strong Lagrangian intermittency throughout the left heart, reflecting the complex and unsteady nature of cardiovascular flow. The present work underscores the sensitivity of Lagrangian statistics to physiological parameters and highlights their potential for improving the understanding of pathological flow conditions in cardiovascular systems. Such Lagrangian tool provides a statistical foundation for modeling shear-induced damage in red blood cells (hemolysis), with implications for the evaluation of prosthetic valves and blood-contacting medical devices. |
| title | Lagrangian analysis of turbulent blood flow in the human left heart |
| topic | Fluid Dynamics |
| url | https://arxiv.org/abs/2506.09708 |