Machine Learning-Based Quantification of Vesicoureteral Reflux with Enhancing Accuracy and Efficiency

Fuente: arXiv
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Autori principali: Alqaraleh, Muhyeeddin, Alzboon, Mowafaq Salem, Al-Batah, Mohammad Subhi, Aesa, Lana Yasin Al, Abu-Arqoub, Mohammed Hasan, Marie, Rashiq Rafiq, Alsmad, Firas Hussein
Natura: Preprint
Pubblicazione: 2025
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author Alqaraleh, Muhyeeddin
Alzboon, Mowafaq Salem
Al-Batah, Mohammad Subhi
Aesa, Lana Yasin Al
Abu-Arqoub, Mohammed Hasan
Marie, Rashiq Rafiq
Alsmad, Firas Hussein
author_facet Alqaraleh, Muhyeeddin
Alzboon, Mowafaq Salem
Al-Batah, Mohammad Subhi
Aesa, Lana Yasin Al
Abu-Arqoub, Mohammed Hasan
Marie, Rashiq Rafiq
Alsmad, Firas Hussein
contents Vesicoureteral reflux (VUR) is traditionally assessed using subjective grading systems, which introduces variability in diagnosis. This study investigates the use of machine learning to improve diagnostic consistency by analyzing voiding cystourethrogram (VCUG) images. A total of 113 VCUG images were reviewed, with expert grading of VUR severity. Nine image-based features were selected to train six predictive models: Logistic Regression, Decision Tree, Gradient Boosting, Neural Network, and Stochastic Gradient Descent. The models were evaluated using leave-one-out cross-validation. Analysis identified deformation patterns in the renal calyces as key indicators of high-grade VUR. All models achieved accurate classifications with no false positives or negatives. High sensitivity to subtle image patterns characteristic of different VUR grades was confirmed by substantial Area Under the Curve (AUC) values. The results suggest that machine learning can offer an objective and standardized alternative to current subjective VUR assessments. These findings highlight renal calyceal deformation as a strong predictor of severe cases. Future research should aim to expand the dataset, refine imaging features, and improve model generalizability for broader clinical use.
format Preprint
id arxiv_https___arxiv_org_abs_2506_11508
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Machine Learning-Based Quantification of Vesicoureteral Reflux with Enhancing Accuracy and Efficiency
Alqaraleh, Muhyeeddin
Alzboon, Mowafaq Salem
Al-Batah, Mohammad Subhi
Aesa, Lana Yasin Al
Abu-Arqoub, Mohammed Hasan
Marie, Rashiq Rafiq
Alsmad, Firas Hussein
Machine Learning
Artificial Intelligence
Vesicoureteral reflux (VUR) is traditionally assessed using subjective grading systems, which introduces variability in diagnosis. This study investigates the use of machine learning to improve diagnostic consistency by analyzing voiding cystourethrogram (VCUG) images. A total of 113 VCUG images were reviewed, with expert grading of VUR severity. Nine image-based features were selected to train six predictive models: Logistic Regression, Decision Tree, Gradient Boosting, Neural Network, and Stochastic Gradient Descent. The models were evaluated using leave-one-out cross-validation. Analysis identified deformation patterns in the renal calyces as key indicators of high-grade VUR. All models achieved accurate classifications with no false positives or negatives. High sensitivity to subtle image patterns characteristic of different VUR grades was confirmed by substantial Area Under the Curve (AUC) values. The results suggest that machine learning can offer an objective and standardized alternative to current subjective VUR assessments. These findings highlight renal calyceal deformation as a strong predictor of severe cases. Future research should aim to expand the dataset, refine imaging features, and improve model generalizability for broader clinical use.
title Machine Learning-Based Quantification of Vesicoureteral Reflux with Enhancing Accuracy and Efficiency
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2506.11508