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Autori principali: Bu, Lehu, Yu, Zhaohan, Lin, Shaoting, Fuhg, Jan N., Yang, Jin
Natura: Preprint
Pubblicazione: 2025
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Accesso online:https://arxiv.org/abs/2506.11936
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author Bu, Lehu
Yu, Zhaohan
Lin, Shaoting
Fuhg, Jan N.
Yang, Jin
author_facet Bu, Lehu
Yu, Zhaohan
Lin, Shaoting
Fuhg, Jan N.
Yang, Jin
contents Laser-induced inertial cavitation (LIC)-where microscale vapor bubbles nucleate due to a focused high-energy pulsed laser and then violently collapse under surrounding high local pressures-offers a unique opportunity to investigate soft biological material mechanics at extremely high strain rates (>1000 1/s). Traditional rheological tools are often limited in these regimes by loading speed, resolution, or invasiveness. Here we introduce novel machine learning (ML) based microrheological frameworks that leverage LIC to characterize the viscoelastic properties of biological materials at ultra-high strain rates. We utilize ultra-high-speed imaging to capture time-resolved bubble radius dynamics during LIC events in various soft viscoelastic materials. These bubble radius versus time measurements are then analyzed using a newly developed Bubble Dynamics Transformer (BDT), a neural network trained on physics-based simulation data. The BDT accurately infers material viscoelastic parameters, eliminating the need for iterative fitting or complex inversion processes. This enables fast, accurate, and non-contact characterization of soft materials under extreme loading conditions, with significant implications for biomedical applications and materials science.
format Preprint
id arxiv_https___arxiv_org_abs_2506_11936
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Bubble Dynamics Transformer: Microrheology at Ultra-High Strain Rates
Bu, Lehu
Yu, Zhaohan
Lin, Shaoting
Fuhg, Jan N.
Yang, Jin
Fluid Dynamics
Materials Science
Machine Learning
Laser-induced inertial cavitation (LIC)-where microscale vapor bubbles nucleate due to a focused high-energy pulsed laser and then violently collapse under surrounding high local pressures-offers a unique opportunity to investigate soft biological material mechanics at extremely high strain rates (>1000 1/s). Traditional rheological tools are often limited in these regimes by loading speed, resolution, or invasiveness. Here we introduce novel machine learning (ML) based microrheological frameworks that leverage LIC to characterize the viscoelastic properties of biological materials at ultra-high strain rates. We utilize ultra-high-speed imaging to capture time-resolved bubble radius dynamics during LIC events in various soft viscoelastic materials. These bubble radius versus time measurements are then analyzed using a newly developed Bubble Dynamics Transformer (BDT), a neural network trained on physics-based simulation data. The BDT accurately infers material viscoelastic parameters, eliminating the need for iterative fitting or complex inversion processes. This enables fast, accurate, and non-contact characterization of soft materials under extreme loading conditions, with significant implications for biomedical applications and materials science.
title Bubble Dynamics Transformer: Microrheology at Ultra-High Strain Rates
topic Fluid Dynamics
Materials Science
Machine Learning
url https://arxiv.org/abs/2506.11936