Explaining Recovery Trajectories of Older Adults Post Lower-Limb Fracture Using Modality-wise Multiview Clustering and Large Language Models

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Main Authors: Khan, Shehroz S., Abedi, Ali, Chu, Charlene H.
Format: Preprint
Published: 2025
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author Khan, Shehroz S.
Abedi, Ali
Chu, Charlene H.
author_facet Khan, Shehroz S.
Abedi, Ali
Chu, Charlene H.
contents Interpreting large volumes of high-dimensional, unlabeled data in a manner that is comprehensible to humans remains a significant challenge across various domains. In unsupervised healthcare data analysis, interpreting clustered data can offer meaningful insights into patients' health outcomes, which hold direct implications for healthcare providers. This paper addresses the problem of interpreting clustered sensor data collected from older adult patients recovering from lower-limb fractures in the community. A total of 560 days of multimodal sensor data, including acceleration, step count, ambient motion, GPS location, heart rate, and sleep, alongside clinical scores, were remotely collected from patients at home. Clustering was first carried out separately for each data modality to assess the impact of feature sets extracted from each modality on patients' recovery trajectories. Then, using context-aware prompting, a large language model was employed to infer meaningful cluster labels for the clusters derived from each modality. The quality of these clusters and their corresponding labels was validated through rigorous statistical testing and visualization against clinical scores collected alongside the multimodal sensor data. The results demonstrated the statistical significance of most modality-specific cluster labels generated by the large language model with respect to clinical scores, confirming the efficacy of the proposed method for interpreting sensor data in an unsupervised manner. This unsupervised data analysis approach, relying solely on sensor data, enables clinicians to identify at-risk patients and take timely measures to improve health outcomes.
format Preprint
id arxiv_https___arxiv_org_abs_2506_12156
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Explaining Recovery Trajectories of Older Adults Post Lower-Limb Fracture Using Modality-wise Multiview Clustering and Large Language Models
Khan, Shehroz S.
Abedi, Ali
Chu, Charlene H.
Machine Learning
Artificial Intelligence
Computer Vision and Pattern Recognition
Interpreting large volumes of high-dimensional, unlabeled data in a manner that is comprehensible to humans remains a significant challenge across various domains. In unsupervised healthcare data analysis, interpreting clustered data can offer meaningful insights into patients' health outcomes, which hold direct implications for healthcare providers. This paper addresses the problem of interpreting clustered sensor data collected from older adult patients recovering from lower-limb fractures in the community. A total of 560 days of multimodal sensor data, including acceleration, step count, ambient motion, GPS location, heart rate, and sleep, alongside clinical scores, were remotely collected from patients at home. Clustering was first carried out separately for each data modality to assess the impact of feature sets extracted from each modality on patients' recovery trajectories. Then, using context-aware prompting, a large language model was employed to infer meaningful cluster labels for the clusters derived from each modality. The quality of these clusters and their corresponding labels was validated through rigorous statistical testing and visualization against clinical scores collected alongside the multimodal sensor data. The results demonstrated the statistical significance of most modality-specific cluster labels generated by the large language model with respect to clinical scores, confirming the efficacy of the proposed method for interpreting sensor data in an unsupervised manner. This unsupervised data analysis approach, relying solely on sensor data, enables clinicians to identify at-risk patients and take timely measures to improve health outcomes.
title Explaining Recovery Trajectories of Older Adults Post Lower-Limb Fracture Using Modality-wise Multiview Clustering and Large Language Models
topic Machine Learning
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2506.12156