Non-reciprocal interactions reshape cells in a model for symbiosis

Fuente: arXiv
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Hauptverfasser: Muñoz-Basagoiti, Maitane, Wassermair, Michael, Amaral, Miguel, Baum, Buzz, Šarić, Anđela
Format: Preprint
Veröffentlicht: 2025
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author Muñoz-Basagoiti, Maitane
Wassermair, Michael
Amaral, Miguel
Baum, Buzz
Šarić, Anđela
author_facet Muñoz-Basagoiti, Maitane
Wassermair, Michael
Amaral, Miguel
Baum, Buzz
Šarić, Anđela
contents The shape of a cell influences and it is influenced by interactions with its neighbouring partners. Here, we introduce a coarse-grained model of non-reciprocal interactions between single-cell organisms to study emergent morphologies during symbiotic association. We show that the cell membrane can be remodelled into branched protrusions, invaginations, transient blebs and other dynamical phases that depend on the number of interacting partners, the asymmetry, and the magnitude of partnership activity. Our model finds a dynamical feedback between the local deformation of the membrane and its driving force, leading to morphologies not accessible to reciprocal systems.
format Preprint
id arxiv_https___arxiv_org_abs_2506_13299
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Non-reciprocal interactions reshape cells in a model for symbiosis
Muñoz-Basagoiti, Maitane
Wassermair, Michael
Amaral, Miguel
Baum, Buzz
Šarić, Anđela
Soft Condensed Matter
Biological Physics
Computational Physics
The shape of a cell influences and it is influenced by interactions with its neighbouring partners. Here, we introduce a coarse-grained model of non-reciprocal interactions between single-cell organisms to study emergent morphologies during symbiotic association. We show that the cell membrane can be remodelled into branched protrusions, invaginations, transient blebs and other dynamical phases that depend on the number of interacting partners, the asymmetry, and the magnitude of partnership activity. Our model finds a dynamical feedback between the local deformation of the membrane and its driving force, leading to morphologies not accessible to reciprocal systems.
title Non-reciprocal interactions reshape cells in a model for symbiosis
topic Soft Condensed Matter
Biological Physics
Computational Physics
url https://arxiv.org/abs/2506.13299