Seq2Bind Webserver for Decoding Binding Hotspots directly from Sequences using Fine-Tuned Protein Language Models
Fuente:
arXiv
Saved in:
| Main Authors: | Ma, Xiang, Dey, Supantha, SR, Vaishnavey, Zelinski, Casey, Li, Qi, Chowdhury, Ratul |
|---|---|
| Format: | Preprint |
| Published: |
2025
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
Twin Peaks: Dual-Head Architecture for Structure-Free Prediction of Protein-Protein Binding Affinity and Mutation Effects
by: Dey, Supantha, et al.
Published: (2025)
by: Dey, Supantha, et al.
Published: (2025)
ProtT-Affinity: Sequence-Based Protein-Protein Binding Affinity Prediction Using ProtT5 Embeddings
by: Lou, Hongfu
Published: (2025)
by: Lou, Hongfu
Published: (2025)
Binding Free Energies without Alchemy
by: Brocidiacono, Michael, et al.
Published: (2026)
by: Brocidiacono, Michael, et al.
Published: (2026)
Topological Machine Learning for Protein-Nucleic Acid Binding Affinity Changes Upon Mutation
by: Liu, Xiang, et al.
Published: (2025)
by: Liu, Xiang, et al.
Published: (2025)
CAP: Commutative Algebra Prediction of Protein-Nucleic Acid Binding Affinities
by: Zia, Mushal, et al.
Published: (2025)
by: Zia, Mushal, et al.
Published: (2025)
MolBind: Multimodal Alignment of Language, Molecules, and Proteins
by: Xiao, Teng, et al.
Published: (2024)
by: Xiao, Teng, et al.
Published: (2024)
Enhancing Protein-Ligand Binding Affinity Predictions using Neural Network Potentials
by: Zariquiey, Francesc Sabanes, et al.
Published: (2024)
by: Zariquiey, Francesc Sabanes, et al.
Published: (2024)
BAPULM: Binding Affinity Prediction using Language Models
by: Meda, Radheesh Sharma, et al.
Published: (2024)
by: Meda, Radheesh Sharma, et al.
Published: (2024)
Leveraging Retrieval-Augmented Generation and Large Language Models to Predict SERCA-Binding Protein Fragments from Cardiac Proteomics Data
by: Phillips, Taylor A, et al.
Published: (2025)
by: Phillips, Taylor A, et al.
Published: (2025)
Hierarchical Contrastive Learning for Multi-Domain Protein-Ligand Binding
by: Zhang, Shuo, et al.
Published: (2026)
by: Zhang, Shuo, et al.
Published: (2026)
DualBind: A Dual-Loss Framework for Protein-Ligand Binding Affinity Prediction
by: Liu, Meng, et al.
Published: (2024)
by: Liu, Meng, et al.
Published: (2024)
SeqProFT: Sequence-only Protein Property Prediction with LoRA Finetuning
by: Zhang, Shuo, et al.
Published: (2024)
by: Zhang, Shuo, et al.
Published: (2024)
AgentPLM: Agentic Protein Language Models with Reasoning-Augmented Decoding for Protein Sequence Design
by: Rahman, Sahil, et al.
Published: (2026)
by: Rahman, Sahil, et al.
Published: (2026)
Sequence-Only Prediction of Binding Affinity Changes: A Robust and Interpretable Model for Antibody Engineering
by: Liu, Chen, et al.
Published: (2025)
by: Liu, Chen, et al.
Published: (2025)
Interpretable Multimodal Learning for Tumor Protein-Metal Binding: Progress, Challenges, and Perspectives
by: Liu, Xiaokun, et al.
Published: (2025)
by: Liu, Xiaokun, et al.
Published: (2025)
Binding SNOMED-CT Terms to Archetype Elements: Establishing a Baseline of Results
by: Berges, Idoia, et al.
Published: (2024)
by: Berges, Idoia, et al.
Published: (2024)
PLA-SGCN: Protein-Ligand Binding Affinity Prediction by Integrating Similar Pairs and Semi-supervised Graph Convolutional Network
by: Abbasi, Karim, et al.
Published: (2024)
by: Abbasi, Karim, et al.
Published: (2024)
On Machine Learning Approaches for Protein-Ligand Binding Affinity Prediction
by: Schapin, Nikolai, et al.
Published: (2024)
by: Schapin, Nikolai, et al.
Published: (2024)
Automated Protein Motif Localization using Concept Activation Vectors in Protein Language Model Embedding Space
by: Shamail, Ahmad, et al.
Published: (2025)
by: Shamail, Ahmad, et al.
Published: (2025)
PhysioSeq2Seq: A Hybrid Physiological Digital Twin and Sequence-to-Sequence LSTM for Long-Horizon Glucose Forecasting in Type 1 Diabetes
by: Tran, Phat, et al.
Published: (2026)
by: Tran, Phat, et al.
Published: (2026)
AbAffinity: A Large Language Model for Predicting Antibody Binding Affinity against SARS-CoV-2
by: Ashraf, Faisal Bin, et al.
Published: (2026)
by: Ashraf, Faisal Bin, et al.
Published: (2026)
VibeProteinBench: An Evaluation Benchmark for Language-interfaced Vibe Protein Design
by: Seo, Hyunjin, et al.
Published: (2026)
by: Seo, Hyunjin, et al.
Published: (2026)
A Multi-Grained Symmetric Differential Equation Model for Learning Protein-Ligand Binding Dynamics
by: Liu, Shengchao, et al.
Published: (2024)
by: Liu, Shengchao, et al.
Published: (2024)
PRISM: Enhancing Protein Inverse Folding through Fine-Grained Retrieval on Structure-Sequence Multimodal Representations
by: Mahbub, Sazan, et al.
Published: (2025)
by: Mahbub, Sazan, et al.
Published: (2025)
Llama-Affinity: A Predictive Antibody Antigen Binding Model Integrating Antibody Sequences with Llama3 Backbone Architecture
by: Hossain, Delower, et al.
Published: (2025)
by: Hossain, Delower, et al.
Published: (2025)
FusionDTI: Fine-grained Binding Discovery with Token-level Fusion for Drug-Target Interaction
by: Meng, Zhaohan, et al.
Published: (2024)
by: Meng, Zhaohan, et al.
Published: (2024)
Investigating Knowledge Distillation Through Neural Networks for Protein Binding Affinity Prediction
by: Abbasi, Wajid Arshad, et al.
Published: (2026)
by: Abbasi, Wajid Arshad, et al.
Published: (2026)
VenusFactory: A Unified Platform for Protein Engineering Data Retrieval and Language Model Fine-Tuning
by: Tan, Yang, et al.
Published: (2025)
by: Tan, Yang, et al.
Published: (2025)
Binding Affinity Prediction: From Conventional to Machine Learning-Based Approaches
by: Liu, Xuefeng, et al.
Published: (2024)
by: Liu, Xuefeng, et al.
Published: (2024)
Scaling and Data Saturation in Protein Language Models
by: Spinner, Aviv, et al.
Published: (2025)
by: Spinner, Aviv, et al.
Published: (2025)
Detection of circular permutations by Protein Language Models
by: Hu, Yue, et al.
Published: (2024)
by: Hu, Yue, et al.
Published: (2024)
VARIANT: Web Server for Decoding and Analyzing Viral Mutations at Genome and Protein Levels
by: Wang, Rui, et al.
Published: (2026)
by: Wang, Rui, et al.
Published: (2026)
LiveProteinBench: A Contamination-Free Benchmark for Assessing Models' Specialized Capabilities in Protein Science
by: Rong, Dingyi, et al.
Published: (2025)
by: Rong, Dingyi, et al.
Published: (2025)
Frequency-Space Mechanics: A Sequence and Coordinate-Free Representation for Protein Function Prediction
by: Reilly, Charles B
Published: (2026)
by: Reilly, Charles B
Published: (2026)
AutoProteinEngine: A Large Language Model Driven Agent Framework for Multimodal AutoML in Protein Engineering
by: Liu, Yungeng, et al.
Published: (2024)
by: Liu, Yungeng, et al.
Published: (2024)
Scoring-Assisted Generative Exploration for Proteins (SAGE-Prot): A Framework for Multi-Objective Protein Optimization via Iterative Sequence Generation and Evaluation
by: Lim, Hocheol, et al.
Published: (2025)
by: Lim, Hocheol, et al.
Published: (2025)
Large Language Model is Secretly a Protein Sequence Optimizer
by: Wang, Yinkai, et al.
Published: (2025)
by: Wang, Yinkai, et al.
Published: (2025)
Brain Tumor Segmentation in Sub-Sahara Africa with Advanced Transformer and ConvNet Methods: Fine-Tuning, Data Mixing and Ensembling
by: Musah, Toufiq, et al.
Published: (2025)
by: Musah, Toufiq, et al.
Published: (2025)
ProT-GFDM: A Generative Fractional Diffusion Model for Protein Generation
by: Liang, Xiao, et al.
Published: (2025)
by: Liang, Xiao, et al.
Published: (2025)
Evolution and Pathogenicity of SARS-CoVs: A Microcanonical Analysis of Receptor-Binding Motifs
by: Frigori, Rafael B.
Published: (2025)
by: Frigori, Rafael B.
Published: (2025)
Similar Items
-
Twin Peaks: Dual-Head Architecture for Structure-Free Prediction of Protein-Protein Binding Affinity and Mutation Effects
by: Dey, Supantha, et al.
Published: (2025) -
ProtT-Affinity: Sequence-Based Protein-Protein Binding Affinity Prediction Using ProtT5 Embeddings
by: Lou, Hongfu
Published: (2025) -
Binding Free Energies without Alchemy
by: Brocidiacono, Michael, et al.
Published: (2026) -
Topological Machine Learning for Protein-Nucleic Acid Binding Affinity Changes Upon Mutation
by: Liu, Xiang, et al.
Published: (2025) -
CAP: Commutative Algebra Prediction of Protein-Nucleic Acid Binding Affinities
by: Zia, Mushal, et al.
Published: (2025)