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Main Authors: Eity, Sumshun Nahar, Afif, Mahin Montasir, Fairooz, Tanisha, Ahmmed, Md. Mortuza, Miah, Md Saef Ullah
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2506.14367
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author Eity, Sumshun Nahar
Afif, Mahin Montasir
Fairooz, Tanisha
Ahmmed, Md. Mortuza
Miah, Md Saef Ullah
author_facet Eity, Sumshun Nahar
Afif, Mahin Montasir
Fairooz, Tanisha
Ahmmed, Md. Mortuza
Miah, Md Saef Ullah
contents Accurate diagnosis of brain disorders such as Alzheimer's disease and brain tumors remains a critical challenge in medical imaging. Conventional methods based on manual MRI analysis are often inefficient and error-prone. To address this, we propose DGG-XNet, a hybrid deep learning model integrating VGG16 and DenseNet121 to enhance feature extraction and classification. DenseNet121 promotes feature reuse and efficient gradient flow through dense connectivity, while VGG16 contributes strong hierarchical spatial representations. Their fusion enables robust multiclass classification of neurological conditions. Grad-CAM is applied to visualize salient regions, enhancing model transparency. Trained on a combined dataset from BraTS 2021 and Kaggle, DGG-XNet achieved a test accuracy of 91.33\%, with precision, recall, and F1-score all exceeding 91\%. These results highlight DGG-XNet's potential as an effective and interpretable tool for computer-aided diagnosis (CAD) of neurodegenerative and oncological brain disorders.
format Preprint
id arxiv_https___arxiv_org_abs_2506_14367
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle DGG-XNet: A Hybrid Deep Learning Framework for Multi-Class Brain Disease Classification with Explainable AI
Eity, Sumshun Nahar
Afif, Mahin Montasir
Fairooz, Tanisha
Ahmmed, Md. Mortuza
Miah, Md Saef Ullah
Computer Vision and Pattern Recognition
Accurate diagnosis of brain disorders such as Alzheimer's disease and brain tumors remains a critical challenge in medical imaging. Conventional methods based on manual MRI analysis are often inefficient and error-prone. To address this, we propose DGG-XNet, a hybrid deep learning model integrating VGG16 and DenseNet121 to enhance feature extraction and classification. DenseNet121 promotes feature reuse and efficient gradient flow through dense connectivity, while VGG16 contributes strong hierarchical spatial representations. Their fusion enables robust multiclass classification of neurological conditions. Grad-CAM is applied to visualize salient regions, enhancing model transparency. Trained on a combined dataset from BraTS 2021 and Kaggle, DGG-XNet achieved a test accuracy of 91.33\%, with precision, recall, and F1-score all exceeding 91\%. These results highlight DGG-XNet's potential as an effective and interpretable tool for computer-aided diagnosis (CAD) of neurodegenerative and oncological brain disorders.
title DGG-XNet: A Hybrid Deep Learning Framework for Multi-Class Brain Disease Classification with Explainable AI
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2506.14367