SynPo: Boosting Training-Free Few-Shot Medical Segmentation via High-Quality Negative Prompts

Fuente: arXiv
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Autores principales: Liu, Yufei, Xiao, Haoke, Chai, Jiaxing, Zhang, Yongcun, Wang, Rong, Meng, Zijie, Luo, Zhiming
Formato: Preprint
Publicado: 2025
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author Liu, Yufei
Xiao, Haoke
Chai, Jiaxing
Zhang, Yongcun
Wang, Rong
Meng, Zijie
Luo, Zhiming
author_facet Liu, Yufei
Xiao, Haoke
Chai, Jiaxing
Zhang, Yongcun
Wang, Rong
Meng, Zijie
Luo, Zhiming
contents The advent of Large Vision Models (LVMs) offers new opportunities for few-shot medical image segmentation. However, existing training-free methods based on LVMs fail to effectively utilize negative prompts, leading to poor performance on low-contrast medical images. To address this issue, we propose SynPo, a training-free few-shot method based on LVMs (e.g., SAM), with the core insight: improving the quality of negative prompts. To select point prompts in a more reliable confidence map, we design a novel Confidence Map Synergy Module by combining the strengths of DINOv2 and SAM. Based on the confidence map, we select the top-k pixels as the positive points set and choose the negative points set using a Gaussian distribution, followed by independent K-means clustering for both sets. Then, these selected points are leveraged as high-quality prompts for SAM to get the segmentation results. Extensive experiments demonstrate that SynPo achieves performance comparable to state-of-the-art training-based few-shot methods.
format Preprint
id arxiv_https___arxiv_org_abs_2506_15153
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle SynPo: Boosting Training-Free Few-Shot Medical Segmentation via High-Quality Negative Prompts
Liu, Yufei
Xiao, Haoke
Chai, Jiaxing
Zhang, Yongcun
Wang, Rong
Meng, Zijie
Luo, Zhiming
Computer Vision and Pattern Recognition
The advent of Large Vision Models (LVMs) offers new opportunities for few-shot medical image segmentation. However, existing training-free methods based on LVMs fail to effectively utilize negative prompts, leading to poor performance on low-contrast medical images. To address this issue, we propose SynPo, a training-free few-shot method based on LVMs (e.g., SAM), with the core insight: improving the quality of negative prompts. To select point prompts in a more reliable confidence map, we design a novel Confidence Map Synergy Module by combining the strengths of DINOv2 and SAM. Based on the confidence map, we select the top-k pixels as the positive points set and choose the negative points set using a Gaussian distribution, followed by independent K-means clustering for both sets. Then, these selected points are leveraged as high-quality prompts for SAM to get the segmentation results. Extensive experiments demonstrate that SynPo achieves performance comparable to state-of-the-art training-based few-shot methods.
title SynPo: Boosting Training-Free Few-Shot Medical Segmentation via High-Quality Negative Prompts
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2506.15153