Dynamics of attractor transitions in Boolean networks under noise

Fuente: arXiv
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Autori principali: Min, Byungjoon, Choi, Jeehye, Laubenbacher, Reinhard
Natura: Preprint
Pubblicazione: 2025
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author Min, Byungjoon
Choi, Jeehye
Laubenbacher, Reinhard
author_facet Min, Byungjoon
Choi, Jeehye
Laubenbacher, Reinhard
contents Biological systems operate under persistent noise, which can alter system states and induce transitions between attractors. Here, we study the attractor dynamics of Boolean networks focusing on the transitions between attractors induced by noise. By computing transition probabilities between attractors, we present methods at the attractor level to determine dominance, stability, and diversity of attractors, and systematically compare local and global noise. Whereas global noise leads to attractor behavior dictated primarily by basin sizes, local noise produces structured transition patterns characterized by enhanced stability, non-trivial dominance patterns, and broader exploration of the attractor space. Our work offers insight into the dynamics of attractors, showing the importance of transition patterns under noise.
format Preprint
id arxiv_https___arxiv_org_abs_2506_15581
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Dynamics of attractor transitions in Boolean networks under noise
Min, Byungjoon
Choi, Jeehye
Laubenbacher, Reinhard
Molecular Networks
Biological systems operate under persistent noise, which can alter system states and induce transitions between attractors. Here, we study the attractor dynamics of Boolean networks focusing on the transitions between attractors induced by noise. By computing transition probabilities between attractors, we present methods at the attractor level to determine dominance, stability, and diversity of attractors, and systematically compare local and global noise. Whereas global noise leads to attractor behavior dictated primarily by basin sizes, local noise produces structured transition patterns characterized by enhanced stability, non-trivial dominance patterns, and broader exploration of the attractor space. Our work offers insight into the dynamics of attractors, showing the importance of transition patterns under noise.
title Dynamics of attractor transitions in Boolean networks under noise
topic Molecular Networks
url https://arxiv.org/abs/2506.15581