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Hauptverfasser: Li, Deyi, Yao, Zijun, Liang, Muxuan, Liu, Mei
Format: Preprint
Veröffentlicht: 2025
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Online-Zugang:https://arxiv.org/abs/2506.15809
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author Li, Deyi
Yao, Zijun
Liang, Muxuan
Liu, Mei
author_facet Li, Deyi
Yao, Zijun
Liang, Muxuan
Liu, Mei
contents In recent years, graph learning has gained significant interest for modeling complex interactions among medical events in structured Electronic Health Record (EHR) data. However, existing graph-based approaches often work in a static manner, either restricting interactions within individual encounters or collapsing all historical encounters into a single snapshot. As a result, when it is necessary to identify meaningful groups of medical events spanning longitudinal encounters, existing methods are inadequate in modeling interactions cross encounters while accounting for temporal dependencies. To address this limitation, we introduce Deep Patient Journey (DeepJ), a novel graph convolutional transformer model with differentiable graph pooling to effectively capture intra-encounter and inter-encounter medical event interactions. DeepJ can identify groups of temporally and functionally related medical events, offering valuable insights into key event clusters pertinent to patient outcome prediction. DeepJ significantly outperformed five state-of-the-art baseline models while enhancing interpretability, demonstrating its potential for improved patient risk stratification.
format Preprint
id arxiv_https___arxiv_org_abs_2506_15809
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle DeepJ: Graph Convolutional Transformers with Differentiable Pooling for Patient Trajectory Modeling
Li, Deyi
Yao, Zijun
Liang, Muxuan
Liu, Mei
Machine Learning
In recent years, graph learning has gained significant interest for modeling complex interactions among medical events in structured Electronic Health Record (EHR) data. However, existing graph-based approaches often work in a static manner, either restricting interactions within individual encounters or collapsing all historical encounters into a single snapshot. As a result, when it is necessary to identify meaningful groups of medical events spanning longitudinal encounters, existing methods are inadequate in modeling interactions cross encounters while accounting for temporal dependencies. To address this limitation, we introduce Deep Patient Journey (DeepJ), a novel graph convolutional transformer model with differentiable graph pooling to effectively capture intra-encounter and inter-encounter medical event interactions. DeepJ can identify groups of temporally and functionally related medical events, offering valuable insights into key event clusters pertinent to patient outcome prediction. DeepJ significantly outperformed five state-of-the-art baseline models while enhancing interpretability, demonstrating its potential for improved patient risk stratification.
title DeepJ: Graph Convolutional Transformers with Differentiable Pooling for Patient Trajectory Modeling
topic Machine Learning
url https://arxiv.org/abs/2506.15809