Historical Report Guided Bi-modal Concurrent Learning for Pathology Report Generation
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arXiv
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| Auteurs principaux: | , , , |
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| Format: | Preprint |
| Publié: |
2025
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| _version_ | 1866918068191494144 |
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| author | Zhang, Ling Yun, Boxiang Li, Qingli Wang, Yan |
| author_facet | Zhang, Ling Yun, Boxiang Li, Qingli Wang, Yan |
| contents | Automated pathology report generation from Whole Slide Images (WSIs) faces two key challenges: (1) lack of semantic content in visual features and (2) inherent information redundancy in WSIs. To address these issues, we propose a novel Historical Report Guided \textbf{Bi}-modal Concurrent Learning Framework for Pathology Report \textbf{Gen}eration (BiGen) emulating pathologists' diagnostic reasoning, consisting of: (1) A knowledge retrieval mechanism to provide rich semantic content, which retrieves WSI-relevant knowledge from pre-built medical knowledge bank by matching high-attention patches and (2) A bi-modal concurrent learning strategy instantiated via a learnable visual token and a learnable textual token to dynamically extract key visual features and retrieved knowledge, where weight-shared layers enable cross-modal alignment between visual features and knowledge features. Our multi-modal decoder integrates both modals for comprehensive diagnostic reports generation. Experiments on the PathText (BRCA) dataset demonstrate our framework's superiority, achieving state-of-the-art performance with 7.4\% relative improvement in NLP metrics and 19.1\% enhancement in classification metrics for Her-2 prediction versus existing methods. Ablation studies validate the necessity of our proposed modules, highlighting our method's ability to provide WSI-relevant rich semantic content and suppress information redundancy in WSIs. Code is publicly available at https://github.com/DeepMed-Lab-ECNU/BiGen. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2506_18658 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Historical Report Guided Bi-modal Concurrent Learning for Pathology Report Generation Zhang, Ling Yun, Boxiang Li, Qingli Wang, Yan Computer Vision and Pattern Recognition Artificial Intelligence Automated pathology report generation from Whole Slide Images (WSIs) faces two key challenges: (1) lack of semantic content in visual features and (2) inherent information redundancy in WSIs. To address these issues, we propose a novel Historical Report Guided \textbf{Bi}-modal Concurrent Learning Framework for Pathology Report \textbf{Gen}eration (BiGen) emulating pathologists' diagnostic reasoning, consisting of: (1) A knowledge retrieval mechanism to provide rich semantic content, which retrieves WSI-relevant knowledge from pre-built medical knowledge bank by matching high-attention patches and (2) A bi-modal concurrent learning strategy instantiated via a learnable visual token and a learnable textual token to dynamically extract key visual features and retrieved knowledge, where weight-shared layers enable cross-modal alignment between visual features and knowledge features. Our multi-modal decoder integrates both modals for comprehensive diagnostic reports generation. Experiments on the PathText (BRCA) dataset demonstrate our framework's superiority, achieving state-of-the-art performance with 7.4\% relative improvement in NLP metrics and 19.1\% enhancement in classification metrics for Her-2 prediction versus existing methods. Ablation studies validate the necessity of our proposed modules, highlighting our method's ability to provide WSI-relevant rich semantic content and suppress information redundancy in WSIs. Code is publicly available at https://github.com/DeepMed-Lab-ECNU/BiGen. |
| title | Historical Report Guided Bi-modal Concurrent Learning for Pathology Report Generation |
| topic | Computer Vision and Pattern Recognition Artificial Intelligence |
| url | https://arxiv.org/abs/2506.18658 |