Style-Aligned Image Composition for Robust Detection of Abnormal Cells in Cytopathology

Fuente: arXiv
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Autori principali: Qi, Qiuyi, Li, Xin, Kong, Ming, Xu, Zikang, Chen, Bingdi, Zhu, Qiang, Zhou, S Kevin
Natura: Preprint
Pubblicazione: 2025
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author Qi, Qiuyi
Li, Xin
Kong, Ming
Xu, Zikang
Chen, Bingdi
Zhu, Qiang
Zhou, S Kevin
author_facet Qi, Qiuyi
Li, Xin
Kong, Ming
Xu, Zikang
Chen, Bingdi
Zhu, Qiang
Zhou, S Kevin
contents Challenges such as the lack of high-quality annotations, long-tailed data distributions, and inconsistent staining styles pose significant obstacles to training neural networks to detect abnormal cells in cytopathology robustly. This paper proposes a style-aligned image composition (SAIC) method that composes high-fidelity and style-preserved pathological images to enhance the effectiveness and robustness of detection models. Without additional training, SAIC first selects an appropriate candidate from the abnormal cell bank based on attribute guidance. Then, it employs a high-frequency feature reconstruction to achieve a style-aligned and high-fidelity composition of abnormal cells and pathological backgrounds. Finally, it introduces a large vision-language model to filter high-quality synthesis images. Experimental results demonstrate that incorporating SAIC-synthesized images effectively enhances the performance and robustness of abnormal cell detection for tail categories and styles, thereby improving overall detection performance. The comprehensive quality evaluation further confirms the generalizability and practicality of SAIC in clinical application scenarios. Our code will be released at https://github.com/Joey-Qi/SAIC.
format Preprint
id arxiv_https___arxiv_org_abs_2506_21001
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Style-Aligned Image Composition for Robust Detection of Abnormal Cells in Cytopathology
Qi, Qiuyi
Li, Xin
Kong, Ming
Xu, Zikang
Chen, Bingdi
Zhu, Qiang
Zhou, S Kevin
Computer Vision and Pattern Recognition
Challenges such as the lack of high-quality annotations, long-tailed data distributions, and inconsistent staining styles pose significant obstacles to training neural networks to detect abnormal cells in cytopathology robustly. This paper proposes a style-aligned image composition (SAIC) method that composes high-fidelity and style-preserved pathological images to enhance the effectiveness and robustness of detection models. Without additional training, SAIC first selects an appropriate candidate from the abnormal cell bank based on attribute guidance. Then, it employs a high-frequency feature reconstruction to achieve a style-aligned and high-fidelity composition of abnormal cells and pathological backgrounds. Finally, it introduces a large vision-language model to filter high-quality synthesis images. Experimental results demonstrate that incorporating SAIC-synthesized images effectively enhances the performance and robustness of abnormal cell detection for tail categories and styles, thereby improving overall detection performance. The comprehensive quality evaluation further confirms the generalizability and practicality of SAIC in clinical application scenarios. Our code will be released at https://github.com/Joey-Qi/SAIC.
title Style-Aligned Image Composition for Robust Detection of Abnormal Cells in Cytopathology
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2506.21001