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Autores principales: Wang, Jing, Sra, Amar, Weiss, Jeremy C.
Formato: Preprint
Publicado: 2025
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Acceso en línea:https://arxiv.org/abs/2506.22444
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author Wang, Jing
Sra, Amar
Weiss, Jeremy C.
author_facet Wang, Jing
Sra, Amar
Weiss, Jeremy C.
contents The long-term effects of Postacute Sequelae of SARS-CoV-2, known as PASC, pose a significant challenge to healthcare systems worldwide. Accurate identification of progression events, such as hospitalization and reinfection, is essential for effective patient management and resource allocation. However, traditional models trained on structured data struggle to capture the nuanced progression of PASC. In this study, we introduce the first publicly available cohort of 18 PASC patients, with text time series features based on Large Language Model Llama-3.1-70B-Instruct and clinical risk annotated by clinical expert. We propose an Active Attention Network to predict the clinical risk and identify progression events related to the risk. By integrating human expertise with active learning, we aim to enhance clinical risk prediction accuracy and enable progression events identification with fewer number of annotation. The ultimate goal is to improves patient care and decision-making for SARS-CoV-2 patient.
format Preprint
id arxiv_https___arxiv_org_abs_2506_22444
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Active Learning for Forecasting Severity among Patients with Post Acute Sequelae of SARS-CoV-2
Wang, Jing
Sra, Amar
Weiss, Jeremy C.
Machine Learning
Computers and Society
The long-term effects of Postacute Sequelae of SARS-CoV-2, known as PASC, pose a significant challenge to healthcare systems worldwide. Accurate identification of progression events, such as hospitalization and reinfection, is essential for effective patient management and resource allocation. However, traditional models trained on structured data struggle to capture the nuanced progression of PASC. In this study, we introduce the first publicly available cohort of 18 PASC patients, with text time series features based on Large Language Model Llama-3.1-70B-Instruct and clinical risk annotated by clinical expert. We propose an Active Attention Network to predict the clinical risk and identify progression events related to the risk. By integrating human expertise with active learning, we aim to enhance clinical risk prediction accuracy and enable progression events identification with fewer number of annotation. The ultimate goal is to improves patient care and decision-making for SARS-CoV-2 patient.
title Active Learning for Forecasting Severity among Patients with Post Acute Sequelae of SARS-CoV-2
topic Machine Learning
Computers and Society
url https://arxiv.org/abs/2506.22444