PlanTUS: A heuristic tool for prospective planning of transcranial ultrasound transducer placements

Fuente: arXiv
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Autores principales: Lueckel, Maximilian, Vijayakumar, Suhas, Bergmann, Til Ole
Formato: Preprint
Publicado: 2025
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author Lueckel, Maximilian
Vijayakumar, Suhas
Bergmann, Til Ole
author_facet Lueckel, Maximilian
Vijayakumar, Suhas
Bergmann, Til Ole
contents Low-intensity focused transcranial ultrasonic stimulation (TUS) offers unique depth and precision in non-invasive brain stimulation. Effective administration of TUS, however, requires precise placement of transducers to ensure selective neural target exposure and engagement. This process is constrained by individual skull anatomy, hardware limitations, as well as computational and time costs of running exhaustive acoustic simulations to optimize transducer placement. To address these challenges, we introduce PlanTUS, a fast, open-source tool designed to heuristically identify feasible transducer positions, accounting for individual anatomical and hardware constraints. It visualizes relevant metrics on the scalp, such as target accessibility, required transducer tilt, and skull thickness, allowing users to identify and export potential transducer positions compatible with both acoustic simulation and neuronavigation software. In addition to individualized planning, PlanTUS facilitates feasibility evaluations during study planning, offering practical utility to researchers seeking to optimize TUS delivery with greater efficiency and precision.
format Preprint
id arxiv_https___arxiv_org_abs_2506_22563
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle PlanTUS: A heuristic tool for prospective planning of transcranial ultrasound transducer placements
Lueckel, Maximilian
Vijayakumar, Suhas
Bergmann, Til Ole
Biological Physics
Low-intensity focused transcranial ultrasonic stimulation (TUS) offers unique depth and precision in non-invasive brain stimulation. Effective administration of TUS, however, requires precise placement of transducers to ensure selective neural target exposure and engagement. This process is constrained by individual skull anatomy, hardware limitations, as well as computational and time costs of running exhaustive acoustic simulations to optimize transducer placement. To address these challenges, we introduce PlanTUS, a fast, open-source tool designed to heuristically identify feasible transducer positions, accounting for individual anatomical and hardware constraints. It visualizes relevant metrics on the scalp, such as target accessibility, required transducer tilt, and skull thickness, allowing users to identify and export potential transducer positions compatible with both acoustic simulation and neuronavigation software. In addition to individualized planning, PlanTUS facilitates feasibility evaluations during study planning, offering practical utility to researchers seeking to optimize TUS delivery with greater efficiency and precision.
title PlanTUS: A heuristic tool for prospective planning of transcranial ultrasound transducer placements
topic Biological Physics
url https://arxiv.org/abs/2506.22563