Diversity by Design: Addressing Mode Collapse Improves scRNA-seq Perturbation Modeling on Well-Calibrated Metrics

Fuente: arXiv

Salvato in:

Dettagli Bibliografici
Autori principali:	Mejia, Gabriel M., Miller, Henry E., Leblanc, Francis J. A., Wang, Bo, Swain, Brendan, Camillo, Lucas Paulo de Lima
Natura:	Preprint
Pubblicazione:	2025
Soggetti:	Genomics Machine Learning Molecular Networks
Accesso online:	Acceder al recurso
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!

Documenti analoghi

Simultaneously Infer Cell Pseudotime,Velocity Field and Gene Interaction from Multi-Branch scRNA-seq Data with scPN
di: Zhou, Zhen, et al.
Pubblicazione: (2024)

scX: A user-friendly tool for scRNA-seq exploration
di: Waichman, Tomás Vega, et al.
Pubblicazione: (2023)

Mix-Geneformer: Unified Representation Learning for Human and Mouse scRNA-seq Data
di: Nishio, Yuki, et al.
Pubblicazione: (2025)

Partial domain adaptation enables cross domain cell type annotation between scRNA-seq and snRNA-seq
di: Chen, Xiran, et al.
Pubblicazione: (2025)

scReader: Prompting Large Language Models to Interpret scRNA-seq Data
di: Li, Cong, et al.
Pubblicazione: (2024)

Global Ground Metric Learning with Applications to scRNA data
di: Kühn, Damin, et al.
Pubblicazione: (2025)

scInterpreter: Training Large Language Models to Interpret scRNA-seq Data for Cell Type Annotation
di: Li, Cong, et al.
Pubblicazione: (2024)

A Hybrid Computational Intelligence Framework for scRNA-seq Imputation: Integrating scRecover and Random Forests
di: Anaissi, Ali, et al.
Pubblicazione: (2025)

Modeling Temporal scRNA-seq Data with Latent Gaussian Process and Optimal Transport
di: Balik, Mehmet Yigit, et al.
Pubblicazione: (2026)

Bipartite Graph Attention-based Clustering for Large-scale scRNA-seq Data
di: Liang, Zhuomin, et al.
Pubblicazione: (2026)

Meta-analysis of scRNA-seq data for choroidal endothelial cells in dry Age-related Macular Degeneration
di: Veksler, Kyle M., et al.
Pubblicazione: (2026)

Hypergraph Representations of scRNA-seq Data for Improved Clustering with Random Walks
di: He, Wan, et al.
Pubblicazione: (2025)

LapDDPM: A Conditional Graph Diffusion Model for scRNA-seq Generation with Spectral Adversarial Perturbations
di: Bini, Lorenzo, et al.
Pubblicazione: (2025)

SpaDiT: Diffusion Transformer for Spatial Gene Expression Prediction using scRNA-seq
di: Li, Xiaoyu, et al.
Pubblicazione: (2024)

Pan-cancer gene set discovery via scRNA-seq for optimal deep learning based downstream tasks
di: Kim, Jong Hyun, et al.
Pubblicazione: (2024)

Graph Structure Learning for Tumor Microenvironment with Cell Type Annotation from non-spatial scRNA-seq data
di: Huang, Yu-An, et al.
Pubblicazione: (2025)

ScAtt: an Attention based architecture to analyze Alzheimer's disease at cell type level from single-cell RNA-sequencing data
di: Liu, Xiaoxia, et al.
Pubblicazione: (2024)

Prevalence of Constitutional Pathogenic Variant in a Cohort of 348 Patients With Multiple Primary Cancer Addressed in Oncogenetic Consultation
di: Mathis Lepage, et al.
Pubblicazione: (2025)

De Novo HNRNPU Pathogenic Variant Related to Developmental Epileptic Encephalopathy With Inherited KANSL1 Loss‐of‐Function Variant Resolved by RNA Analysis
di: Daria Akimova, et al.
Pubblicazione: (2025)

scBench: Evaluating AI Agents on Single-Cell RNA-seq Analysis
di: Workman, Kenny, et al.
Pubblicazione: (2026)

ltirloni/Ixsc-scRNA-seq: Ixsc-scRNA-seq
di: Lucas Tirloni
Pubblicazione: (2026)

The Environment-Dependent Regulatory Landscape of the E. coli Genome
di: Röschinger, Tom, et al.
Pubblicazione: (2025)

Approaches for benchmarking single-cell gene regulatory network inference methods
di: Uzun, Yasin
Pubblicazione: (2023)

Multilayer network approaches to omics data integration in Digital Twins for cancer research
di: Chenel, Hugo, et al.
Pubblicazione: (2024)

Computational strategies for cross-species knowledge transfer
di: Yuan, Hao, et al.
Pubblicazione: (2024)

Mechanism of Quercetin in Inhibiting Triple-Negative Breast Cancer by Regulating T Cell-Related Targets: An Analysis Based on Single-Cell Sequencing and Network Pharmacology
di: Chen, Ruiqi, et al.
Pubblicazione: (2025)

Multiscale Modeling Primer: Focus on Chromatin and Epigenetics
di: Mahajan, Achal, et al.
Pubblicazione: (2025)

Annotated genome of the Atlantic dog whelk, Nucella lapillus.
di: Ford, Meghan R, et al.
Pubblicazione: (2025)

Reference genome for the benthic marine diatom Psammoneis japonica: Bacterial associations and repeat-driven genome size evolution in diatoms.
di: Roberts, Wade R, et al.
Pubblicazione: (2025)

scRDiT: Generating single-cell RNA-seq data by diffusion transformers and accelerating sampling
di: Dong, Shengze, et al.
Pubblicazione: (2024)

Homozygous TREM2 c.549del; p.(Leu184Serfs*5) variant causing Nasu‐Hakola disease in three siblings in a consanguineous Iraqi family: Case report and review of literature
di: Naser Gilani, et al.
Pubblicazione: (2024)

Novel LAMA1 Mutations in a Pedigree With Poretti‐Boltshauser Syndrome: Implications for Hypomyelination
di: Si Huang, et al.
Pubblicazione: (2026)

Clinical report and genetic analysis of rare premature infant nephronophthisis caused by biallelic TTC21B variants
di: Yingying Li, et al.
Pubblicazione: (2024)

Novel De Novo Intronic Variant of SYNGAP1 Associated With the Neurodevelopmental Disorders
di: Wuming Xie, et al.
Pubblicazione: (2025)

Clinical characteristics of a case of multiple mitochondrial dysfunction syndrome 3
di: Hai Xu, et al.
Pubblicazione: (2024)

Historical Control Analysis Demonstrates Greater Long‐Term Reduction in Plasma Globotriaosylceramide (Gb3) by Venglustat Compared With Placebo or Agalsidase Beta in Male Patients With Classic Fabry Disease
di: Dominique P. Germain, et al.
Pubblicazione: (2025)

Correction to “Analysis of the clinical and genetic characteristics of a Chinese family with osteogenesis imperfecta type I”
Pubblicazione: (2024)

The Functions and Implications of MicroRNAs in Premature Ovarian Insufficiency
di: Hui Gao, et al.
Pubblicazione: (2025)

Prenatal Diagnosis of Autosomal Recessive Primary Microcephaly Type 2 Caused by Compound Heterozygous WDR62 Variants in a Family With Two Recurrent Cases
di: Yan‐Fang Li, et al.
Pubblicazione: (2026)

A De Novo Frameshift Variant in SMC1A Causes Non‐Classic Cornelia de Lange Syndrome With Epilepsy: A Case Report and Literature Review
di: Ying Yang, et al.
Pubblicazione: (2025)