_version_ 1866915366510264320
author Zhou, Yang
Quek, Chrystie Wan Ning
Zhou, Jun
Wang, Yan
Bai, Yang
Ke, Yuhe
Yao, Jie
Gutierrez, Laura
Teo, Zhen Ling
Ting, Darren Shu Jeng
Soetikno, Brian T.
Nielsen, Christopher S.
Elze, Tobias
Li, Zengxiang
Dinh, Linh Le
Cheng, Lionel Tim-Ee
Anh, Tran Nguyen Tuan
Cheng, Chee Leong
Wong, Tien Yin
Liu, Nan
Tan, Iain Beehuat
Lim, Tony Kiat Hon
Goh, Rick Siow Mong
Liu, Yong
Ting, Daniel Shu Wei
author_facet Zhou, Yang
Quek, Chrystie Wan Ning
Zhou, Jun
Wang, Yan
Bai, Yang
Ke, Yuhe
Yao, Jie
Gutierrez, Laura
Teo, Zhen Ling
Ting, Darren Shu Jeng
Soetikno, Brian T.
Nielsen, Christopher S.
Elze, Tobias
Li, Zengxiang
Dinh, Linh Le
Cheng, Lionel Tim-Ee
Anh, Tran Nguyen Tuan
Cheng, Chee Leong
Wong, Tien Yin
Liu, Nan
Tan, Iain Beehuat
Lim, Tony Kiat Hon
Goh, Rick Siow Mong
Liu, Yong
Ting, Daniel Shu Wei
contents Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training these models typically requires large, labour-intensive, well-labelled datasets. We developed MerMED-FM, a state-of-the-art multimodal, multi-specialty foundation model trained using self-supervised learning and a memory module. MerMED-FM was trained on 3.3 million medical images from over ten specialties and seven modalities, including computed tomography (CT), chest X-rays (CXR), ultrasound (US), pathology patches, color fundus photography (CFP), optical coherence tomography (OCT) and dermatology images. MerMED-FM was evaluated across multiple diseases and compared against existing foundational models. Strong performance was achieved across all modalities, with AUROCs of 0.988 (OCT); 0.982 (pathology); 0.951 (US); 0.943 (CT); 0.931 (skin); 0.894 (CFP); 0.858 (CXR). MerMED-FM has the potential to be a highly adaptable, versatile, cross-specialty foundation model that enables robust medical imaging interpretation across diverse medical disciplines.
format Preprint
id arxiv_https___arxiv_org_abs_2507_00185
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Multimodal, Multi-Disease Medical Imaging Foundation Model (MerMED-FM)
Zhou, Yang
Quek, Chrystie Wan Ning
Zhou, Jun
Wang, Yan
Bai, Yang
Ke, Yuhe
Yao, Jie
Gutierrez, Laura
Teo, Zhen Ling
Ting, Darren Shu Jeng
Soetikno, Brian T.
Nielsen, Christopher S.
Elze, Tobias
Li, Zengxiang
Dinh, Linh Le
Cheng, Lionel Tim-Ee
Anh, Tran Nguyen Tuan
Cheng, Chee Leong
Wong, Tien Yin
Liu, Nan
Tan, Iain Beehuat
Lim, Tony Kiat Hon
Goh, Rick Siow Mong
Liu, Yong
Ting, Daniel Shu Wei
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training these models typically requires large, labour-intensive, well-labelled datasets. We developed MerMED-FM, a state-of-the-art multimodal, multi-specialty foundation model trained using self-supervised learning and a memory module. MerMED-FM was trained on 3.3 million medical images from over ten specialties and seven modalities, including computed tomography (CT), chest X-rays (CXR), ultrasound (US), pathology patches, color fundus photography (CFP), optical coherence tomography (OCT) and dermatology images. MerMED-FM was evaluated across multiple diseases and compared against existing foundational models. Strong performance was achieved across all modalities, with AUROCs of 0.988 (OCT); 0.982 (pathology); 0.951 (US); 0.943 (CT); 0.931 (skin); 0.894 (CFP); 0.858 (CXR). MerMED-FM has the potential to be a highly adaptable, versatile, cross-specialty foundation model that enables robust medical imaging interpretation across diverse medical disciplines.
title Multimodal, Multi-Disease Medical Imaging Foundation Model (MerMED-FM)
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2507.00185