Quantum Approximate Optimization Algorithm for Spatiotemporal Forecasting of HIV Clusters
Fuente:
arXiv
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Preprint |
| Published: |
2025
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1866911032067227648 |
|---|---|
| author | Roosan, Don Nirzhor, Saif Khan, Rubayat Hai, Fahmida Haidar, Mohammad Rifat |
| author_facet | Roosan, Don Nirzhor, Saif Khan, Rubayat Hai, Fahmida Haidar, Mohammad Rifat |
| contents | HIV epidemiological data is increasingly complex, requiring advanced computation for accurate cluster detection and forecasting. We employed quantum-accelerated machine learning to analyze HIV prevalence at the ZIP-code level using AIDSVu and synthetic SDoH data for 2022. Our approach compared classical clustering (DBSCAN, HDBSCAN) with a quantum approximate optimization algorithm (QAOA), developed a hybrid quantum-classical neural network for HIV prevalence forecasting, and used quantum Bayesian networks to explore causal links between SDoH factors and HIV incidence. The QAOA-based method achieved 92% accuracy in cluster detection within 1.6 seconds, outperforming classical algorithms. Meanwhile, the hybrid quantum-classical neural network predicted HIV prevalence with 94% accuracy, surpassing a purely classical counterpart. Quantum Bayesian analysis identified housing instability as a key driver of HIV cluster emergence and expansion, with stigma exerting a geographically variable influence. These quantum-enhanced methods deliver greater precision and efficiency in HIV surveillance while illuminating critical causal pathways. This work can guide targeted interventions, optimize resource allocation for PrEP, and address structural inequities fueling HIV transmission. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2507_00848 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Quantum Approximate Optimization Algorithm for Spatiotemporal Forecasting of HIV Clusters Roosan, Don Nirzhor, Saif Khan, Rubayat Hai, Fahmida Haidar, Mohammad Rifat Machine Learning Molecular Networks HIV epidemiological data is increasingly complex, requiring advanced computation for accurate cluster detection and forecasting. We employed quantum-accelerated machine learning to analyze HIV prevalence at the ZIP-code level using AIDSVu and synthetic SDoH data for 2022. Our approach compared classical clustering (DBSCAN, HDBSCAN) with a quantum approximate optimization algorithm (QAOA), developed a hybrid quantum-classical neural network for HIV prevalence forecasting, and used quantum Bayesian networks to explore causal links between SDoH factors and HIV incidence. The QAOA-based method achieved 92% accuracy in cluster detection within 1.6 seconds, outperforming classical algorithms. Meanwhile, the hybrid quantum-classical neural network predicted HIV prevalence with 94% accuracy, surpassing a purely classical counterpart. Quantum Bayesian analysis identified housing instability as a key driver of HIV cluster emergence and expansion, with stigma exerting a geographically variable influence. These quantum-enhanced methods deliver greater precision and efficiency in HIV surveillance while illuminating critical causal pathways. This work can guide targeted interventions, optimize resource allocation for PrEP, and address structural inequities fueling HIV transmission. |
| title | Quantum Approximate Optimization Algorithm for Spatiotemporal Forecasting of HIV Clusters |
| topic | Machine Learning Molecular Networks |
| url | https://arxiv.org/abs/2507.00848 |