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Autori principali: Mustafa, Akram, Naseem, Usman, Azghadi, Mostafa Rahimi
Natura: Preprint
Pubblicazione: 2025
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Accesso online:https://arxiv.org/abs/2507.03001
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author Mustafa, Akram
Naseem, Usman
Azghadi, Mostafa Rahimi
author_facet Mustafa, Akram
Naseem, Usman
Azghadi, Mostafa Rahimi
contents This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10 most frequent ICD-10 codes, the study tested 11 LLMs, including models with and without structured reasoning capabilities. Medical terms were extracted using a clinical NLP tool (cTAKES), and models were prompted in a consistent, coder-like format. None of the models achieved an F1 score above 57%, with performance dropping as code specificity increased. Reasoning-based models generally outperformed non-reasoning ones, with Gemini 2.5 Pro performing best overall. Some codes, such as those related to chronic heart disease, were classified more accurately than others. The findings suggest that while LLMs can assist human coders, they are not yet reliable enough for full automation. Future work should explore hybrid methods, domain-specific model training, and the use of structured clinical data.
format Preprint
id arxiv_https___arxiv_org_abs_2507_03001
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Evaluating Hierarchical Clinical Document Classification Using Reasoning-Based LLMs
Mustafa, Akram
Naseem, Usman
Azghadi, Mostafa Rahimi
Computation and Language
Artificial Intelligence
This study evaluates how well large language models (LLMs) can classify ICD-10 codes from hospital discharge summaries, a critical but error-prone task in healthcare. Using 1,500 summaries from the MIMIC-IV dataset and focusing on the 10 most frequent ICD-10 codes, the study tested 11 LLMs, including models with and without structured reasoning capabilities. Medical terms were extracted using a clinical NLP tool (cTAKES), and models were prompted in a consistent, coder-like format. None of the models achieved an F1 score above 57%, with performance dropping as code specificity increased. Reasoning-based models generally outperformed non-reasoning ones, with Gemini 2.5 Pro performing best overall. Some codes, such as those related to chronic heart disease, were classified more accurately than others. The findings suggest that while LLMs can assist human coders, they are not yet reliable enough for full automation. Future work should explore hybrid methods, domain-specific model training, and the use of structured clinical data.
title Evaluating Hierarchical Clinical Document Classification Using Reasoning-Based LLMs
topic Computation and Language
Artificial Intelligence
url https://arxiv.org/abs/2507.03001