MedGemma Technical Report

Fuente: arXiv
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Hauptverfasser: Sellergren, Andrew, Kazemzadeh, Sahar, Jaroensri, Tiam, Kiraly, Atilla, Traverse, Madeleine, Kohlberger, Timo, Xu, Shawn, Jamil, Fayaz, Hughes, Cían, Lau, Charles, Chen, Justin, Mahvar, Fereshteh, Yatziv, Liron, Chen, Tiffany, Sterling, Bram, Baby, Stefanie Anna, Baby, Susanna Maria, Lai, Jeremy, Schmidgall, Samuel, Yang, Lu, Chen, Kejia, Bjornsson, Per, Reddy, Shashir, Brush, Ryan, Philbrick, Kenneth, Asiedu, Mercy, Mezerreg, Ines, Hu, Howard, Yang, Howard, Tiwari, Richa, Jansen, Sunny, Singh, Preeti, Liu, Yun, Azizi, Shekoofeh, Kamath, Aishwarya, Ferret, Johan, Pathak, Shreya, Vieillard, Nino, Merhej, Ramona, Perrin, Sarah, Matejovicova, Tatiana, Ramé, Alexandre, Riviere, Morgane, Rouillard, Louis, Mesnard, Thomas, Cideron, Geoffrey, Grill, Jean-bastien, Ramos, Sabela, Yvinec, Edouard, Casbon, Michelle, Buchatskaya, Elena, Alayrac, Jean-Baptiste, Lepikhin, Dmitry, Feinberg, Vlad, Borgeaud, Sebastian, Andreev, Alek, Hardin, Cassidy, Dadashi, Robert, Hussenot, Léonard, Joulin, Armand, Bachem, Olivier, Matias, Yossi, Chou, Katherine, Hassidim, Avinatan, Goel, Kavi, Farabet, Clement, Barral, Joelle, Warkentin, Tris, Shlens, Jonathon, Fleet, David, Cotruta, Victor, Sanseviero, Omar, Martins, Gus, Kirk, Phoebe, Rao, Anand, Shetty, Shravya, Steiner, David F., Kirmizibayrak, Can, Pilgrim, Rory, Golden, Daniel, Yang, Lin
Format: Preprint
Veröffentlicht: 2025
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author Sellergren, Andrew
Kazemzadeh, Sahar
Jaroensri, Tiam
Kiraly, Atilla
Traverse, Madeleine
Kohlberger, Timo
Xu, Shawn
Jamil, Fayaz
Hughes, Cían
Lau, Charles
Chen, Justin
Mahvar, Fereshteh
Yatziv, Liron
Chen, Tiffany
Sterling, Bram
Baby, Stefanie Anna
Baby, Susanna Maria
Lai, Jeremy
Schmidgall, Samuel
Yang, Lu
Chen, Kejia
Bjornsson, Per
Reddy, Shashir
Brush, Ryan
Philbrick, Kenneth
Asiedu, Mercy
Mezerreg, Ines
Hu, Howard
Yang, Howard
Tiwari, Richa
Jansen, Sunny
Singh, Preeti
Liu, Yun
Azizi, Shekoofeh
Kamath, Aishwarya
Ferret, Johan
Pathak, Shreya
Vieillard, Nino
Merhej, Ramona
Perrin, Sarah
Matejovicova, Tatiana
Ramé, Alexandre
Riviere, Morgane
Rouillard, Louis
Mesnard, Thomas
Cideron, Geoffrey
Grill, Jean-bastien
Ramos, Sabela
Yvinec, Edouard
Casbon, Michelle
Buchatskaya, Elena
Alayrac, Jean-Baptiste
Lepikhin, Dmitry
Feinberg, Vlad
Borgeaud, Sebastian
Andreev, Alek
Hardin, Cassidy
Dadashi, Robert
Hussenot, Léonard
Joulin, Armand
Bachem, Olivier
Matias, Yossi
Chou, Katherine
Hassidim, Avinatan
Goel, Kavi
Farabet, Clement
Barral, Joelle
Warkentin, Tris
Shlens, Jonathon
Fleet, David
Cotruta, Victor
Sanseviero, Omar
Martins, Gus
Kirk, Phoebe
Rao, Anand
Shetty, Shravya
Steiner, David F.
Kirmizibayrak, Can
Pilgrim, Rory
Golden, Daniel
Yang, Lin
author_facet Sellergren, Andrew
Kazemzadeh, Sahar
Jaroensri, Tiam
Kiraly, Atilla
Traverse, Madeleine
Kohlberger, Timo
Xu, Shawn
Jamil, Fayaz
Hughes, Cían
Lau, Charles
Chen, Justin
Mahvar, Fereshteh
Yatziv, Liron
Chen, Tiffany
Sterling, Bram
Baby, Stefanie Anna
Baby, Susanna Maria
Lai, Jeremy
Schmidgall, Samuel
Yang, Lu
Chen, Kejia
Bjornsson, Per
Reddy, Shashir
Brush, Ryan
Philbrick, Kenneth
Asiedu, Mercy
Mezerreg, Ines
Hu, Howard
Yang, Howard
Tiwari, Richa
Jansen, Sunny
Singh, Preeti
Liu, Yun
Azizi, Shekoofeh
Kamath, Aishwarya
Ferret, Johan
Pathak, Shreya
Vieillard, Nino
Merhej, Ramona
Perrin, Sarah
Matejovicova, Tatiana
Ramé, Alexandre
Riviere, Morgane
Rouillard, Louis
Mesnard, Thomas
Cideron, Geoffrey
Grill, Jean-bastien
Ramos, Sabela
Yvinec, Edouard
Casbon, Michelle
Buchatskaya, Elena
Alayrac, Jean-Baptiste
Lepikhin, Dmitry
Feinberg, Vlad
Borgeaud, Sebastian
Andreev, Alek
Hardin, Cassidy
Dadashi, Robert
Hussenot, Léonard
Joulin, Armand
Bachem, Olivier
Matias, Yossi
Chou, Katherine
Hassidim, Avinatan
Goel, Kavi
Farabet, Clement
Barral, Joelle
Warkentin, Tris
Shlens, Jonathon
Fleet, David
Cotruta, Victor
Sanseviero, Omar
Martins, Gus
Kirk, Phoebe
Rao, Anand
Shetty, Shravya
Steiner, David F.
Kirmizibayrak, Can
Pilgrim, Rory
Golden, Daniel
Yang, Lin
contents Artificial intelligence (AI) has significant potential in healthcare applications, but its training and deployment faces challenges due to healthcare's diverse data, complex tasks, and the need to preserve privacy. Foundation models that perform well on medical tasks and require less task-specific tuning data are critical to accelerate the development of healthcare AI applications. We introduce MedGemma, a collection of medical vision-language foundation models based on Gemma 3 4B and 27B. MedGemma demonstrates advanced medical understanding and reasoning on images and text, significantly exceeding the performance of similar-sized generative models and approaching the performance of task-specific models, while maintaining the general capabilities of the Gemma 3 base models. For out-of-distribution tasks, MedGemma achieves 2.6-10% improvement on medical multimodal question answering, 15.5-18.1% improvement on chest X-ray finding classification, and 10.8% improvement on agentic evaluations compared to the base models. Fine-tuning MedGemma further improves performance in subdomains, reducing errors in electronic health record information retrieval by 50% and reaching comparable performance to existing specialized state-of-the-art methods for pneumothorax classification and histopathology patch classification. We additionally introduce MedSigLIP, a medically-tuned vision encoder derived from SigLIP. MedSigLIP powers the visual understanding capabilities of MedGemma and as an encoder achieves comparable or better performance than specialized medical image encoders. Taken together, the MedGemma collection provides a strong foundation of medical image and text capabilities, with potential to significantly accelerate medical research and development of downstream applications. The MedGemma collection, including tutorials and model weights, can be found at https://goo.gle/medgemma.
format Preprint
id arxiv_https___arxiv_org_abs_2507_05201
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MedGemma Technical Report
Sellergren, Andrew
Kazemzadeh, Sahar
Jaroensri, Tiam
Kiraly, Atilla
Traverse, Madeleine
Kohlberger, Timo
Xu, Shawn
Jamil, Fayaz
Hughes, Cían
Lau, Charles
Chen, Justin
Mahvar, Fereshteh
Yatziv, Liron
Chen, Tiffany
Sterling, Bram
Baby, Stefanie Anna
Baby, Susanna Maria
Lai, Jeremy
Schmidgall, Samuel
Yang, Lu
Chen, Kejia
Bjornsson, Per
Reddy, Shashir
Brush, Ryan
Philbrick, Kenneth
Asiedu, Mercy
Mezerreg, Ines
Hu, Howard
Yang, Howard
Tiwari, Richa
Jansen, Sunny
Singh, Preeti
Liu, Yun
Azizi, Shekoofeh
Kamath, Aishwarya
Ferret, Johan
Pathak, Shreya
Vieillard, Nino
Merhej, Ramona
Perrin, Sarah
Matejovicova, Tatiana
Ramé, Alexandre
Riviere, Morgane
Rouillard, Louis
Mesnard, Thomas
Cideron, Geoffrey
Grill, Jean-bastien
Ramos, Sabela
Yvinec, Edouard
Casbon, Michelle
Buchatskaya, Elena
Alayrac, Jean-Baptiste
Lepikhin, Dmitry
Feinberg, Vlad
Borgeaud, Sebastian
Andreev, Alek
Hardin, Cassidy
Dadashi, Robert
Hussenot, Léonard
Joulin, Armand
Bachem, Olivier
Matias, Yossi
Chou, Katherine
Hassidim, Avinatan
Goel, Kavi
Farabet, Clement
Barral, Joelle
Warkentin, Tris
Shlens, Jonathon
Fleet, David
Cotruta, Victor
Sanseviero, Omar
Martins, Gus
Kirk, Phoebe
Rao, Anand
Shetty, Shravya
Steiner, David F.
Kirmizibayrak, Can
Pilgrim, Rory
Golden, Daniel
Yang, Lin
Artificial Intelligence
Computation and Language
Computer Vision and Pattern Recognition
Artificial intelligence (AI) has significant potential in healthcare applications, but its training and deployment faces challenges due to healthcare's diverse data, complex tasks, and the need to preserve privacy. Foundation models that perform well on medical tasks and require less task-specific tuning data are critical to accelerate the development of healthcare AI applications. We introduce MedGemma, a collection of medical vision-language foundation models based on Gemma 3 4B and 27B. MedGemma demonstrates advanced medical understanding and reasoning on images and text, significantly exceeding the performance of similar-sized generative models and approaching the performance of task-specific models, while maintaining the general capabilities of the Gemma 3 base models. For out-of-distribution tasks, MedGemma achieves 2.6-10% improvement on medical multimodal question answering, 15.5-18.1% improvement on chest X-ray finding classification, and 10.8% improvement on agentic evaluations compared to the base models. Fine-tuning MedGemma further improves performance in subdomains, reducing errors in electronic health record information retrieval by 50% and reaching comparable performance to existing specialized state-of-the-art methods for pneumothorax classification and histopathology patch classification. We additionally introduce MedSigLIP, a medically-tuned vision encoder derived from SigLIP. MedSigLIP powers the visual understanding capabilities of MedGemma and as an encoder achieves comparable or better performance than specialized medical image encoders. Taken together, the MedGemma collection provides a strong foundation of medical image and text capabilities, with potential to significantly accelerate medical research and development of downstream applications. The MedGemma collection, including tutorials and model weights, can be found at https://goo.gle/medgemma.
title MedGemma Technical Report
topic Artificial Intelligence
Computation and Language
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2507.05201