Neural Network-Based Parameter Estimation for Non-Autonomous Differential Equations with Discontinuous Signals

Fuente: arXiv
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Main Authors: Jo, Hyeontae, Josić, Krešimir, Kim, Jae Kyoung
Format: Preprint
Published: 2025
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author Jo, Hyeontae
Josić, Krešimir
Kim, Jae Kyoung
author_facet Jo, Hyeontae
Josić, Krešimir
Kim, Jae Kyoung
contents Non-autonomous differential equations are crucial for modeling systems influenced by external signals, yet fitting these models to data becomes particularly challenging when the signals change abruptly. To address this problem, we propose a novel parameter estimation method utilizing functional approximations with artificial neural networks. Our approach, termed Harmonic Approximation of Discontinuous External Signals using Neural Networks (HADES-NN), operates in two iterated stages. In the first stage, the algorithm employs a neural network to approximate the discontinuous signal with a smooth function. In the second stage, it uses this smooth approximate signal to estimate model parameters. HADES-NN gives highly accurate and precise parameter estimates across various applications, including circadian clock systems regulated by external light inputs measured via wearable devices and the mating response of yeast to external pheromone signals. HADES-NN greatly extends the range of model systems that can be fit to real-world measurements.
format Preprint
id arxiv_https___arxiv_org_abs_2507_06267
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Neural Network-Based Parameter Estimation for Non-Autonomous Differential Equations with Discontinuous Signals
Jo, Hyeontae
Josić, Krešimir
Kim, Jae Kyoung
Machine Learning
34C60, 92B05, 68T07, 93C15, 65K10
Non-autonomous differential equations are crucial for modeling systems influenced by external signals, yet fitting these models to data becomes particularly challenging when the signals change abruptly. To address this problem, we propose a novel parameter estimation method utilizing functional approximations with artificial neural networks. Our approach, termed Harmonic Approximation of Discontinuous External Signals using Neural Networks (HADES-NN), operates in two iterated stages. In the first stage, the algorithm employs a neural network to approximate the discontinuous signal with a smooth function. In the second stage, it uses this smooth approximate signal to estimate model parameters. HADES-NN gives highly accurate and precise parameter estimates across various applications, including circadian clock systems regulated by external light inputs measured via wearable devices and the mating response of yeast to external pheromone signals. HADES-NN greatly extends the range of model systems that can be fit to real-world measurements.
title Neural Network-Based Parameter Estimation for Non-Autonomous Differential Equations with Discontinuous Signals
topic Machine Learning
34C60, 92B05, 68T07, 93C15, 65K10
url https://arxiv.org/abs/2507.06267