MiNAA-WebApp: A Web-Based Tool for the Visualization and Analysis of Microbiome Networks

Fuente: arXiv
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Autori principali: Yang, Qiyao, Aghdam, Rosa, Nelson, Reed, Solís-Lemus, Claudia
Natura: Preprint
Pubblicazione: 2025
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author Yang, Qiyao
Aghdam, Rosa
Nelson, Reed
Solís-Lemus, Claudia
author_facet Yang, Qiyao
Aghdam, Rosa
Nelson, Reed
Solís-Lemus, Claudia
contents Microbial networks, representing microbes as nodes and their interactions as edges, are crucial for understanding community dynamics in various environments. Analyzing microbiome networks is crucial for identifying keystone taxa that play central roles in maintaining microbial community structure and function, assessing how environmental changes such as pollution, climate shifts, or land use affect microbial dynamics, tracking disease progression by revealing alterations in microbial interactions over time, and predicting microbial community responses to interventions such as antibiotics, probiotics, or changes in diet and habitat. The complexity of microbial interactions necessitates the use of computational tools such as the MiNAA-WebApp, available at https://minaa.wid.wisc.edu, which enhances the accessibility of the Microbiome Network Alignment Algorithm MiNAA. This tool allows researchers to align microbial networks and explore ecological relationships and community dynamics without extensive computational skills. Originally, MiNAA's command-line interface limited its usability for those without programming backgrounds. The web-based MiNAA-WebApp addresses this shortcoming by offering an intuitive interface with visualization tools, allowing easy exploration and analysis of microbial networks. The web app is designed for microbiome networks but also applicable to other biological networks, broadening its use in computational biology and making network-based research accessible to a wider audience.
format Preprint
id arxiv_https___arxiv_org_abs_2507_08822
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MiNAA-WebApp: A Web-Based Tool for the Visualization and Analysis of Microbiome Networks
Yang, Qiyao
Aghdam, Rosa
Nelson, Reed
Solís-Lemus, Claudia
Molecular Networks
Microbial networks, representing microbes as nodes and their interactions as edges, are crucial for understanding community dynamics in various environments. Analyzing microbiome networks is crucial for identifying keystone taxa that play central roles in maintaining microbial community structure and function, assessing how environmental changes such as pollution, climate shifts, or land use affect microbial dynamics, tracking disease progression by revealing alterations in microbial interactions over time, and predicting microbial community responses to interventions such as antibiotics, probiotics, or changes in diet and habitat. The complexity of microbial interactions necessitates the use of computational tools such as the MiNAA-WebApp, available at https://minaa.wid.wisc.edu, which enhances the accessibility of the Microbiome Network Alignment Algorithm MiNAA. This tool allows researchers to align microbial networks and explore ecological relationships and community dynamics without extensive computational skills. Originally, MiNAA's command-line interface limited its usability for those without programming backgrounds. The web-based MiNAA-WebApp addresses this shortcoming by offering an intuitive interface with visualization tools, allowing easy exploration and analysis of microbial networks. The web app is designed for microbiome networks but also applicable to other biological networks, broadening its use in computational biology and making network-based research accessible to a wider audience.
title MiNAA-WebApp: A Web-Based Tool for the Visualization and Analysis of Microbiome Networks
topic Molecular Networks
url https://arxiv.org/abs/2507.08822