Numerical Analysis of a Bio-Polymerization Model

Fuente: arXiv
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Auteurs principaux: Balooch, Ali, Courtney-Pahlevani, Faranak, Davis, Lisa, Dunca, Adrian, Neda, Monika, Reyes, Jorge
Format: Preprint
Publié: 2025
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author Balooch, Ali
Courtney-Pahlevani, Faranak
Davis, Lisa
Dunca, Adrian
Neda, Monika
Reyes, Jorge
author_facet Balooch, Ali
Courtney-Pahlevani, Faranak
Davis, Lisa
Dunca, Adrian
Neda, Monika
Reyes, Jorge
contents This work studies a stabilization technique for first-order hyperbolic differential equations used in DNA transcription modeling. Specifically we use the Lighthill-Whitham-Richards Model with a nonlinear Greenshield's velocity proposed in [1]. Standard finite element methods are known to produce spurious oscillations when applied to nonsmooth solutions. To address this, we incorporate stabilization terms involving spatial and temporal filtering into the system. We present numerical stability and prove convergence results for both the backwards Euler and time filtered formulations. We also present several computational results to demonstrate the rates in space and in time as well as for selected biological scenarios.
format Preprint
id arxiv_https___arxiv_org_abs_2507_09921
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Numerical Analysis of a Bio-Polymerization Model
Balooch, Ali
Courtney-Pahlevani, Faranak
Davis, Lisa
Dunca, Adrian
Neda, Monika
Reyes, Jorge
Numerical Analysis
65M12, 65M60, 92-08, 92-10
This work studies a stabilization technique for first-order hyperbolic differential equations used in DNA transcription modeling. Specifically we use the Lighthill-Whitham-Richards Model with a nonlinear Greenshield's velocity proposed in [1]. Standard finite element methods are known to produce spurious oscillations when applied to nonsmooth solutions. To address this, we incorporate stabilization terms involving spatial and temporal filtering into the system. We present numerical stability and prove convergence results for both the backwards Euler and time filtered formulations. We also present several computational results to demonstrate the rates in space and in time as well as for selected biological scenarios.
title Numerical Analysis of a Bio-Polymerization Model
topic Numerical Analysis
65M12, 65M60, 92-08, 92-10
url https://arxiv.org/abs/2507.09921