BenchReAD: A systematic benchmark for retinal anomaly detection

Fuente: arXiv
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Autores principales: Lian, Chenyu, Zhou, Hong-Yu, Hu, Zhanli, Qin, Jing
Formato: Preprint
Publicado: 2025
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author Lian, Chenyu
Zhou, Hong-Yu
Hu, Zhanli
Qin, Jing
author_facet Lian, Chenyu
Zhou, Hong-Yu
Hu, Zhanli
Qin, Jing
contents Retinal anomaly detection plays a pivotal role in screening ocular and systemic diseases. Despite its significance, progress in the field has been hindered by the absence of a comprehensive and publicly available benchmark, which is essential for the fair evaluation and advancement of methodologies. Due to this limitation, previous anomaly detection work related to retinal images has been constrained by (1) a limited and overly simplistic set of anomaly types, (2) test sets that are nearly saturated, and (3) a lack of generalization evaluation, resulting in less convincing experimental setups. Furthermore, existing benchmarks in medical anomaly detection predominantly focus on one-class supervised approaches (training only with negative samples), overlooking the vast amounts of labeled abnormal data and unlabeled data that are commonly available in clinical practice. To bridge these gaps, we introduce a benchmark for retinal anomaly detection, which is comprehensive and systematic in terms of data and algorithm. Through categorizing and benchmarking previous methods, we find that a fully supervised approach leveraging disentangled representations of abnormalities (DRA) achieves the best performance but suffers from significant drops in performance when encountering certain unseen anomalies. Inspired by the memory bank mechanisms in one-class supervised learning, we propose NFM-DRA, which integrates DRA with a Normal Feature Memory to mitigate the performance degradation, establishing a new SOTA. The benchmark is publicly available at https://github.com/DopamineLcy/BenchReAD.
format Preprint
id arxiv_https___arxiv_org_abs_2507_10492
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle BenchReAD: A systematic benchmark for retinal anomaly detection
Lian, Chenyu
Zhou, Hong-Yu
Hu, Zhanli
Qin, Jing
Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
Retinal anomaly detection plays a pivotal role in screening ocular and systemic diseases. Despite its significance, progress in the field has been hindered by the absence of a comprehensive and publicly available benchmark, which is essential for the fair evaluation and advancement of methodologies. Due to this limitation, previous anomaly detection work related to retinal images has been constrained by (1) a limited and overly simplistic set of anomaly types, (2) test sets that are nearly saturated, and (3) a lack of generalization evaluation, resulting in less convincing experimental setups. Furthermore, existing benchmarks in medical anomaly detection predominantly focus on one-class supervised approaches (training only with negative samples), overlooking the vast amounts of labeled abnormal data and unlabeled data that are commonly available in clinical practice. To bridge these gaps, we introduce a benchmark for retinal anomaly detection, which is comprehensive and systematic in terms of data and algorithm. Through categorizing and benchmarking previous methods, we find that a fully supervised approach leveraging disentangled representations of abnormalities (DRA) achieves the best performance but suffers from significant drops in performance when encountering certain unseen anomalies. Inspired by the memory bank mechanisms in one-class supervised learning, we propose NFM-DRA, which integrates DRA with a Normal Feature Memory to mitigate the performance degradation, establishing a new SOTA. The benchmark is publicly available at https://github.com/DopamineLcy/BenchReAD.
title BenchReAD: A systematic benchmark for retinal anomaly detection
topic Computer Vision and Pattern Recognition
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2507.10492