Automated Thematic Analyses Using LLMs: Xylazine Wound Management Social Media Chatter Use Case

Fuente: arXiv
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Auteurs principaux: Hairston, JaMor, Ranjan, Ritvik, Lakamana, Sahithi, Spadaro, Anthony, Bozkurt, Selen, Perrone, Jeanmarie, Sarker, Abeed
Format: Preprint
Publié: 2025
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author Hairston, JaMor
Ranjan, Ritvik
Lakamana, Sahithi
Spadaro, Anthony
Bozkurt, Selen
Perrone, Jeanmarie
Sarker, Abeed
author_facet Hairston, JaMor
Ranjan, Ritvik
Lakamana, Sahithi
Spadaro, Anthony
Bozkurt, Selen
Perrone, Jeanmarie
Sarker, Abeed
contents Background Large language models (LLMs) face challenges in inductive thematic analysis, a task requiring deep interpretive and domain-specific expertise. We evaluated the feasibility of using LLMs to replicate expert-driven thematic analysis of social media data. Methods Using two temporally non-intersecting Reddit datasets on xylazine (n=286 and n=686, for model optimization and validation, respectively) with twelve expert-derived themes, we evaluated five LLMs against expert coding. We modeled the task as a series of binary classifications, rather than a single, multi-label classification, employing zero-, single-, and few-shot prompting strategies and measuring performance via accuracy, precision, recall, and F1-score. Results On the validation set, GPT-4o with two-shot prompting performed best (accuracy: 90.9%; F1-score: 0.71). For high-prevalence themes, model-derived thematic distributions closely mirrored expert classifications (e.g., xylazine use: 13.6% vs. 17.8%; MOUD use: 16.5% vs. 17.8%). Conclusions Our findings suggest that few-shot LLM-based approaches can automate thematic analyses, offering a scalable supplement for qualitative research. Keywords: thematic analysis, large language models, natural language processing, qualitative analysis, social media, prompt engineering, public health
format Preprint
id arxiv_https___arxiv_org_abs_2507_10803
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Automated Thematic Analyses Using LLMs: Xylazine Wound Management Social Media Chatter Use Case
Hairston, JaMor
Ranjan, Ritvik
Lakamana, Sahithi
Spadaro, Anthony
Bozkurt, Selen
Perrone, Jeanmarie
Sarker, Abeed
Artificial Intelligence
Computation and Language
Emerging Technologies
Information Retrieval
Background Large language models (LLMs) face challenges in inductive thematic analysis, a task requiring deep interpretive and domain-specific expertise. We evaluated the feasibility of using LLMs to replicate expert-driven thematic analysis of social media data. Methods Using two temporally non-intersecting Reddit datasets on xylazine (n=286 and n=686, for model optimization and validation, respectively) with twelve expert-derived themes, we evaluated five LLMs against expert coding. We modeled the task as a series of binary classifications, rather than a single, multi-label classification, employing zero-, single-, and few-shot prompting strategies and measuring performance via accuracy, precision, recall, and F1-score. Results On the validation set, GPT-4o with two-shot prompting performed best (accuracy: 90.9%; F1-score: 0.71). For high-prevalence themes, model-derived thematic distributions closely mirrored expert classifications (e.g., xylazine use: 13.6% vs. 17.8%; MOUD use: 16.5% vs. 17.8%). Conclusions Our findings suggest that few-shot LLM-based approaches can automate thematic analyses, offering a scalable supplement for qualitative research. Keywords: thematic analysis, large language models, natural language processing, qualitative analysis, social media, prompt engineering, public health
title Automated Thematic Analyses Using LLMs: Xylazine Wound Management Social Media Chatter Use Case
topic Artificial Intelligence
Computation and Language
Emerging Technologies
Information Retrieval
url https://arxiv.org/abs/2507.10803