Electron-Transfer and Exchange-Interaction Model of the Ligand Hyperfine Structure of Alkylated Iron-Sulfur Clusters

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Main Authors: Robinson, William C., Pascutti, Victoria, Hall, David A., Mosquera, Martín A.
Format: Preprint
Published: 2025
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author Robinson, William C.
Pascutti, Victoria
Hall, David A.
Mosquera, Martín A.
author_facet Robinson, William C.
Pascutti, Victoria
Hall, David A.
Mosquera, Martín A.
contents Iron-sulfur clusters conduct a wide variety of biochemical reactions that are conserved across all domains of life. The hyperfine structure of reactive ligands of these clusters can be studied experimentally and theoretically by means of hyperfine spectroscopy, which can reveal catalytic intermediates in these biochemical processes. Their theoretical prediction, however, requires either advanced methods that describe strongly correlated systems, or Hamiltonian modeling based on symmetry-broken electronic structure methods. This work shows that the addition of electron-transfer interactions to the Heisenberg-Dirac-van Vleck Hamiltonian model leads to the quantitative explanation of hyperfine coupling constants at active organic ligand sites. Comparison with experimentally available results confirms our extended approach can be used in calculations aimed at describing cutting-edge systems.
format Preprint
id arxiv_https___arxiv_org_abs_2507_15838
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Electron-Transfer and Exchange-Interaction Model of the Ligand Hyperfine Structure of Alkylated Iron-Sulfur Clusters
Robinson, William C.
Pascutti, Victoria
Hall, David A.
Mosquera, Martín A.
Chemical Physics
Strongly Correlated Electrons
Iron-sulfur clusters conduct a wide variety of biochemical reactions that are conserved across all domains of life. The hyperfine structure of reactive ligands of these clusters can be studied experimentally and theoretically by means of hyperfine spectroscopy, which can reveal catalytic intermediates in these biochemical processes. Their theoretical prediction, however, requires either advanced methods that describe strongly correlated systems, or Hamiltonian modeling based on symmetry-broken electronic structure methods. This work shows that the addition of electron-transfer interactions to the Heisenberg-Dirac-van Vleck Hamiltonian model leads to the quantitative explanation of hyperfine coupling constants at active organic ligand sites. Comparison with experimentally available results confirms our extended approach can be used in calculations aimed at describing cutting-edge systems.
title Electron-Transfer and Exchange-Interaction Model of the Ligand Hyperfine Structure of Alkylated Iron-Sulfur Clusters
topic Chemical Physics
Strongly Correlated Electrons
url https://arxiv.org/abs/2507.15838