Faithful, Interpretable Chest X-ray Diagnosis with Anti-Aliased B-cos Networks

Fuente: arXiv
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Autori principali: Kleinmann, Marcel, Agnihotri, Shashank, Keuper, Margret
Natura: Preprint
Pubblicazione: 2025
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author Kleinmann, Marcel
Agnihotri, Shashank
Keuper, Margret
author_facet Kleinmann, Marcel
Agnihotri, Shashank
Keuper, Margret
contents Faithfulness and interpretability are essential for deploying deep neural networks (DNNs) in safety-critical domains such as medical imaging. B-cos networks offer a promising solution by replacing standard linear layers with a weight-input alignment mechanism, producing inherently interpretable, class-specific explanations without post-hoc methods. While maintaining diagnostic performance competitive with state-of-the-art DNNs, standard B-cos models suffer from severe aliasing artifacts in their explanation maps, making them unsuitable for clinical use where clarity is essential. In this work, we address these limitations by introducing anti-aliasing strategies using FLCPooling (FLC) and BlurPool (BP) to significantly improve explanation quality. Our experiments on chest X-ray datasets demonstrate that the modified $\text{B-cos}_\text{FLC}$ and $\text{B-cos}_\text{BP}$ preserve strong predictive performance while providing faithful and artifact-free explanations suitable for clinical application in multi-class and multi-label settings. Code available at: GitHub repository (url: https://github.com/mkleinma/B-cos-medical-paper).
format Preprint
id arxiv_https___arxiv_org_abs_2507_16761
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Faithful, Interpretable Chest X-ray Diagnosis with Anti-Aliased B-cos Networks
Kleinmann, Marcel
Agnihotri, Shashank
Keuper, Margret
Computer Vision and Pattern Recognition
Machine Learning
Faithfulness and interpretability are essential for deploying deep neural networks (DNNs) in safety-critical domains such as medical imaging. B-cos networks offer a promising solution by replacing standard linear layers with a weight-input alignment mechanism, producing inherently interpretable, class-specific explanations without post-hoc methods. While maintaining diagnostic performance competitive with state-of-the-art DNNs, standard B-cos models suffer from severe aliasing artifacts in their explanation maps, making them unsuitable for clinical use where clarity is essential. In this work, we address these limitations by introducing anti-aliasing strategies using FLCPooling (FLC) and BlurPool (BP) to significantly improve explanation quality. Our experiments on chest X-ray datasets demonstrate that the modified $\text{B-cos}_\text{FLC}$ and $\text{B-cos}_\text{BP}$ preserve strong predictive performance while providing faithful and artifact-free explanations suitable for clinical application in multi-class and multi-label settings. Code available at: GitHub repository (url: https://github.com/mkleinma/B-cos-medical-paper).
title Faithful, Interpretable Chest X-ray Diagnosis with Anti-Aliased B-cos Networks
topic Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2507.16761