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Main Authors: Lin, Zhengcheng, Ying, Zuobin, Li, Zhenyu, Liu, Zhenyu, Lu, Jian, Ding, Weiping
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2507.17269
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author Lin, Zhengcheng
Ying, Zuobin
Li, Zhenyu
Liu, Zhenyu
Lu, Jian
Ding, Weiping
author_facet Lin, Zhengcheng
Ying, Zuobin
Li, Zhenyu
Liu, Zhenyu
Lu, Jian
Ding, Weiping
contents Early diagnosis and accurate identification of lesion location and progression in prostate cancer (PCa) are critical for assisting clinicians in formulating effective treatment strategies. However, due to the high semantic homogeneity between lesion and non-lesion areas, existing medical image segmentation methods often struggle to accurately comprehend lesion semantics, resulting in the problem of semantic confusion. To address this challenge, we propose a novel Pixel Anchor Module, which guides the model to discover a sparse set of feature anchors that serve to capture and interpret global contextual information. This mechanism enhances the model's nonlinear representation capacity and improves segmentation accuracy within lesion regions. Moreover, we design a self-attention-based Top_k selection strategy to further refine the identification of these feature anchors, and incorporate a focal loss function to mitigate class imbalance, thereby facilitating more precise semantic interpretation across diverse regions. Our method achieves state-of-the-art performance on the PI-CAI dataset, demonstrating 69.73% IoU and 74.32% Dice scores, and significantly improving prostate cancer lesion detection.
format Preprint
id arxiv_https___arxiv_org_abs_2507_17269
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle MyGO: Make your Goals Obvious, Avoiding Semantic Confusion in Prostate Cancer Lesion Region Segmentation
Lin, Zhengcheng
Ying, Zuobin
Li, Zhenyu
Liu, Zhenyu
Lu, Jian
Ding, Weiping
Image and Video Processing
Computer Vision and Pattern Recognition
Early diagnosis and accurate identification of lesion location and progression in prostate cancer (PCa) are critical for assisting clinicians in formulating effective treatment strategies. However, due to the high semantic homogeneity between lesion and non-lesion areas, existing medical image segmentation methods often struggle to accurately comprehend lesion semantics, resulting in the problem of semantic confusion. To address this challenge, we propose a novel Pixel Anchor Module, which guides the model to discover a sparse set of feature anchors that serve to capture and interpret global contextual information. This mechanism enhances the model's nonlinear representation capacity and improves segmentation accuracy within lesion regions. Moreover, we design a self-attention-based Top_k selection strategy to further refine the identification of these feature anchors, and incorporate a focal loss function to mitigate class imbalance, thereby facilitating more precise semantic interpretation across diverse regions. Our method achieves state-of-the-art performance on the PI-CAI dataset, demonstrating 69.73% IoU and 74.32% Dice scores, and significantly improving prostate cancer lesion detection.
title MyGO: Make your Goals Obvious, Avoiding Semantic Confusion in Prostate Cancer Lesion Region Segmentation
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2507.17269