Human-AI Collaboration and Explainability for 2D/3D Registration Quality Assurance

Fuente: arXiv
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Auteurs principaux: Cho, Sue Min, Do, Alexander, Taylor, Russell H., Unberath, Mathias
Format: Preprint
Publié: 2025
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author Cho, Sue Min
Do, Alexander
Taylor, Russell H.
Unberath, Mathias
author_facet Cho, Sue Min
Do, Alexander
Taylor, Russell H.
Unberath, Mathias
contents Purpose: As surgery increasingly integrates advanced imaging, algorithms, and robotics to automate complex tasks, human judgment of system correctness remains a vital safeguard for patient safety. A critical example is 2D/3D registration, where small registration misalignments can lead to surgical errors. Current visualization strategies alone are insufficient to reliably enable humans to detect these misalignments, highlighting the need for enhanced decision-support tools. Methods: We propose the first artificial intelligence (AI) model tailored to 2D/3D registration quality assessment, augmented with explainable AI (XAI) mechanisms to clarify the model's predictions. Using both objective measures (e.g., accuracy, sensitivity, precision, specificity) and subjective evaluations (e.g., workload, trust, and understanding), we systematically compare decision-making across four conditions: AI-only, Human-only, Human+AI, and Human+XAI. Results: The AI-only condition achieved the highest accuracy, whereas collaborative paradigms (Human+AI and Human+XAI) improved sensitivity, precision, and specificity compared to standalone approaches. Participants experienced significantly lower workload in collaborative conditions relative to the Human-only condition. Moreover, participants reported a greater understanding of AI predictions in the Human+XAI condition than in Human+AI, although no significant differences were observed between the two collaborative paradigms in perceived trust or workload. Conclusion: Human-AI collaboration can enhance 2D/3D registration quality assurance, with explainability mechanisms improving user understanding. Future work should refine XAI designs to optimize decision-making performance and efficiency. Extending both the algorithmic design and human-XAI collaboration elements holds promise for more robust quality assurance of 2D/3D registration.
format Preprint
id arxiv_https___arxiv_org_abs_2507_17597
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Human-AI Collaboration and Explainability for 2D/3D Registration Quality Assurance
Cho, Sue Min
Do, Alexander
Taylor, Russell H.
Unberath, Mathias
Human-Computer Interaction
Computer Vision and Pattern Recognition
Purpose: As surgery increasingly integrates advanced imaging, algorithms, and robotics to automate complex tasks, human judgment of system correctness remains a vital safeguard for patient safety. A critical example is 2D/3D registration, where small registration misalignments can lead to surgical errors. Current visualization strategies alone are insufficient to reliably enable humans to detect these misalignments, highlighting the need for enhanced decision-support tools. Methods: We propose the first artificial intelligence (AI) model tailored to 2D/3D registration quality assessment, augmented with explainable AI (XAI) mechanisms to clarify the model's predictions. Using both objective measures (e.g., accuracy, sensitivity, precision, specificity) and subjective evaluations (e.g., workload, trust, and understanding), we systematically compare decision-making across four conditions: AI-only, Human-only, Human+AI, and Human+XAI. Results: The AI-only condition achieved the highest accuracy, whereas collaborative paradigms (Human+AI and Human+XAI) improved sensitivity, precision, and specificity compared to standalone approaches. Participants experienced significantly lower workload in collaborative conditions relative to the Human-only condition. Moreover, participants reported a greater understanding of AI predictions in the Human+XAI condition than in Human+AI, although no significant differences were observed between the two collaborative paradigms in perceived trust or workload. Conclusion: Human-AI collaboration can enhance 2D/3D registration quality assurance, with explainability mechanisms improving user understanding. Future work should refine XAI designs to optimize decision-making performance and efficiency. Extending both the algorithmic design and human-XAI collaboration elements holds promise for more robust quality assurance of 2D/3D registration.
title Human-AI Collaboration and Explainability for 2D/3D Registration Quality Assurance
topic Human-Computer Interaction
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2507.17597