Parameter-Efficient Fine-Tuning of 3D DDPM for MRI Image Generation Using Tensor Networks

Fuente: arXiv
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Main Authors: Li, Binghua, Chang, Ziqing, Liang, Tong, Li, Chao, Tanaka, Toshihisa, Aoki, Shigeki, Zhao, Qibin, Sun, Zhe
Format: Preprint
Published: 2025
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author Li, Binghua
Chang, Ziqing
Liang, Tong
Li, Chao
Tanaka, Toshihisa
Aoki, Shigeki
Zhao, Qibin
Sun, Zhe
author_facet Li, Binghua
Chang, Ziqing
Liang, Tong
Li, Chao
Tanaka, Toshihisa
Aoki, Shigeki
Zhao, Qibin
Sun, Zhe
contents We address the challenge of parameter-efficient fine-tuning (PEFT) for three-dimensional (3D) U-Net-based denoising diffusion probabilistic models (DDPMs) in magnetic resonance imaging (MRI) image generation. Despite its practical significance, research on parameter-efficient representations of 3D convolution operations remains limited. To bridge this gap, we propose Tensor Volumetric Operator (TenVOO), a novel PEFT method specifically designed for fine-tuning DDPMs with 3D convolutional backbones. Leveraging tensor network modeling, TenVOO represents 3D convolution kernels with lower-dimensional tensors, effectively capturing complex spatial dependencies during fine-tuning with few parameters. We evaluate TenVOO on three downstream brain MRI datasets-ADNI, PPMI, and BraTS2021-by fine-tuning a DDPM pretrained on 59,830 T1-weighted brain MRI scans from the UK Biobank. Our results demonstrate that TenVOO achieves state-of-the-art performance in multi-scale structural similarity index measure (MS-SSIM), outperforming existing approaches in capturing spatial dependencies while requiring only 0.3% of the trainable parameters of the original model. Our code is available at: https://github.com/xiaovhua/tenvoo
format Preprint
id arxiv_https___arxiv_org_abs_2507_18112
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Parameter-Efficient Fine-Tuning of 3D DDPM for MRI Image Generation Using Tensor Networks
Li, Binghua
Chang, Ziqing
Liang, Tong
Li, Chao
Tanaka, Toshihisa
Aoki, Shigeki
Zhao, Qibin
Sun, Zhe
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
We address the challenge of parameter-efficient fine-tuning (PEFT) for three-dimensional (3D) U-Net-based denoising diffusion probabilistic models (DDPMs) in magnetic resonance imaging (MRI) image generation. Despite its practical significance, research on parameter-efficient representations of 3D convolution operations remains limited. To bridge this gap, we propose Tensor Volumetric Operator (TenVOO), a novel PEFT method specifically designed for fine-tuning DDPMs with 3D convolutional backbones. Leveraging tensor network modeling, TenVOO represents 3D convolution kernels with lower-dimensional tensors, effectively capturing complex spatial dependencies during fine-tuning with few parameters. We evaluate TenVOO on three downstream brain MRI datasets-ADNI, PPMI, and BraTS2021-by fine-tuning a DDPM pretrained on 59,830 T1-weighted brain MRI scans from the UK Biobank. Our results demonstrate that TenVOO achieves state-of-the-art performance in multi-scale structural similarity index measure (MS-SSIM), outperforming existing approaches in capturing spatial dependencies while requiring only 0.3% of the trainable parameters of the original model. Our code is available at: https://github.com/xiaovhua/tenvoo
title Parameter-Efficient Fine-Tuning of 3D DDPM for MRI Image Generation Using Tensor Networks
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2507.18112