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Main Authors: Wang, Qinyang, Lee, Hoileong, Pu, Xiaodi, Lai, Yuanming, Ma, Yiming
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2507.19566
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author Wang, Qinyang
Lee, Hoileong
Pu, Xiaodi
Lai, Yuanming
Ma, Yiming
author_facet Wang, Qinyang
Lee, Hoileong
Pu, Xiaodi
Lai, Yuanming
Ma, Yiming
contents In clinical medicine, rats are commonly used as experimental subjects. However, their estrous cycle significantly impacts their biological responses, leading to differences in experimental results. Therefore, accurately determining the estrous cycle is crucial for minimizing interference. Manually identifying the estrous cycle in rats presents several challenges, including high costs, long training periods, and subjectivity. To address these issues, this paper proposes a classification network-Spatial Long-distance EfficientNet (SLENet). This network is designed based on EfficientNet, specifically modifying the Mobile Inverted Bottleneck Convolution (MBConv) module by introducing a novel Spatial Efficient Channel Attention (SECA) mechanism to replace the original Squeeze Excitation (SE) module. Additionally, a Non-local attention mechanism is incorporated after the last convolutional layer to enhance the network's ability to capture long-range dependencies. The dataset used 2,655 microscopic images of rat vaginal epithelial cells, with 531 images in the test set. Experimental results indicate that SLENet achieved an accuracy of 96.31%, outperforming baseline EfficientNet model (94.2%). This finding provide practical value for optimizing experimental design in rat-based studies such as reproductive and pharmacological research, but this study is limited to microscopy image data, without considering other factors like temporal patterns, thus, incorporating multi-modal input is necessary for future application.
format Preprint
id arxiv_https___arxiv_org_abs_2507_19566
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle SLENet: A Novel Multiscale CNN-Based Network for Detecting the Rats Estrous Cycle
Wang, Qinyang
Lee, Hoileong
Pu, Xiaodi
Lai, Yuanming
Ma, Yiming
Image and Video Processing
In clinical medicine, rats are commonly used as experimental subjects. However, their estrous cycle significantly impacts their biological responses, leading to differences in experimental results. Therefore, accurately determining the estrous cycle is crucial for minimizing interference. Manually identifying the estrous cycle in rats presents several challenges, including high costs, long training periods, and subjectivity. To address these issues, this paper proposes a classification network-Spatial Long-distance EfficientNet (SLENet). This network is designed based on EfficientNet, specifically modifying the Mobile Inverted Bottleneck Convolution (MBConv) module by introducing a novel Spatial Efficient Channel Attention (SECA) mechanism to replace the original Squeeze Excitation (SE) module. Additionally, a Non-local attention mechanism is incorporated after the last convolutional layer to enhance the network's ability to capture long-range dependencies. The dataset used 2,655 microscopic images of rat vaginal epithelial cells, with 531 images in the test set. Experimental results indicate that SLENet achieved an accuracy of 96.31%, outperforming baseline EfficientNet model (94.2%). This finding provide practical value for optimizing experimental design in rat-based studies such as reproductive and pharmacological research, but this study is limited to microscopy image data, without considering other factors like temporal patterns, thus, incorporating multi-modal input is necessary for future application.
title SLENet: A Novel Multiscale CNN-Based Network for Detecting the Rats Estrous Cycle
topic Image and Video Processing
url https://arxiv.org/abs/2507.19566