Privacy-Preserving AI for Encrypted Medical Imaging: A Framework for Secure Diagnosis and Learning

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Hauptverfasser: Siam, Abdullah Al, Shohan, Sadequzzaman
Format: Preprint
Veröffentlicht: 2025
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author Siam, Abdullah Al
Shohan, Sadequzzaman
author_facet Siam, Abdullah Al
Shohan, Sadequzzaman
contents The rapid integration of Artificial Intelligence (AI) into medical diagnostics has raised pressing concerns about patient privacy, especially when sensitive imaging data must be transferred, stored, or processed. In this paper, we propose a novel framework for privacy-preserving diagnostic inference on encrypted medical images using a modified convolutional neural network (Masked-CNN) capable of operating on transformed or ciphered image formats. Our approach leverages AES-CBC encryption coupled with JPEG2000 compression to protect medical images while maintaining their suitability for AI inference. We evaluate the system using public DICOM datasets (NIH ChestX-ray14 and LIDC-IDRI), focusing on diagnostic accuracy, inference latency, storage efficiency, and privacy leakage resistance. Experimental results show that the encrypted inference model achieves performance comparable to its unencrypted counterpart, with only marginal trade-offs in accuracy and latency. The proposed framework bridges the gap between data privacy and clinical utility, offering a practical, scalable solution for secure AI-driven diagnostics.
format Preprint
id arxiv_https___arxiv_org_abs_2507_21060
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Privacy-Preserving AI for Encrypted Medical Imaging: A Framework for Secure Diagnosis and Learning
Siam, Abdullah Al
Shohan, Sadequzzaman
Cryptography and Security
Artificial Intelligence
Image and Video Processing
The rapid integration of Artificial Intelligence (AI) into medical diagnostics has raised pressing concerns about patient privacy, especially when sensitive imaging data must be transferred, stored, or processed. In this paper, we propose a novel framework for privacy-preserving diagnostic inference on encrypted medical images using a modified convolutional neural network (Masked-CNN) capable of operating on transformed or ciphered image formats. Our approach leverages AES-CBC encryption coupled with JPEG2000 compression to protect medical images while maintaining their suitability for AI inference. We evaluate the system using public DICOM datasets (NIH ChestX-ray14 and LIDC-IDRI), focusing on diagnostic accuracy, inference latency, storage efficiency, and privacy leakage resistance. Experimental results show that the encrypted inference model achieves performance comparable to its unencrypted counterpart, with only marginal trade-offs in accuracy and latency. The proposed framework bridges the gap between data privacy and clinical utility, offering a practical, scalable solution for secure AI-driven diagnostics.
title Privacy-Preserving AI for Encrypted Medical Imaging: A Framework for Secure Diagnosis and Learning
topic Cryptography and Security
Artificial Intelligence
Image and Video Processing
url https://arxiv.org/abs/2507.21060