Depth-resolved polarisation sensitive optical coherence tomography reveals the complex microanatomical response of cartilage to compression
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arXiv
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| Auteurs principaux: | , , , , , , , |
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| Format: | Preprint |
| Publié: |
2025
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| _version_ | 1866913964426788864 |
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| author | Tharan, Darven Murali Bonesi, Marco Everett, Daniel Goodwin, Matthew McGoverin, Cushla McGlashan, Sue Thambyah, Ashvin Vanholsbeeck, Frédérique |
| author_facet | Tharan, Darven Murali Bonesi, Marco Everett, Daniel Goodwin, Matthew McGoverin, Cushla McGlashan, Sue Thambyah, Ashvin Vanholsbeeck, Frédérique |
| contents | Conventional methods for analysing cartilage microstructure under mechanical loading are largely destructive. In this work, we evaluate the efficacy of using depth-resolved polarisation sensitive optical coherence tomography (PS-OCT) to study the cartilage morphological response to compression. We show that depth-resolved PS-OCT reveals the microstructure of cartilage under load, and it can do so non-destructively, opening significant possibilities for enhanced clinical assessment of cartilage health by detecting deviance from normal load-bearing behaviour. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2507_21427 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Depth-resolved polarisation sensitive optical coherence tomography reveals the complex microanatomical response of cartilage to compression Tharan, Darven Murali Bonesi, Marco Everett, Daniel Goodwin, Matthew McGoverin, Cushla McGlashan, Sue Thambyah, Ashvin Vanholsbeeck, Frédérique Optics Medical Physics Conventional methods for analysing cartilage microstructure under mechanical loading are largely destructive. In this work, we evaluate the efficacy of using depth-resolved polarisation sensitive optical coherence tomography (PS-OCT) to study the cartilage morphological response to compression. We show that depth-resolved PS-OCT reveals the microstructure of cartilage under load, and it can do so non-destructively, opening significant possibilities for enhanced clinical assessment of cartilage health by detecting deviance from normal load-bearing behaviour. |
| title | Depth-resolved polarisation sensitive optical coherence tomography reveals the complex microanatomical response of cartilage to compression |
| topic | Optics Medical Physics |
| url | https://arxiv.org/abs/2507.21427 |