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Main Authors: Wang, Kaixuan, Diao, Chenxin, Jacques, Jason T., Guo, Zhongliang, Zhao, Shuai
Format: Preprint
Published: 2025
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Online Access:https://arxiv.org/abs/2507.21815
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author Wang, Kaixuan
Diao, Chenxin
Jacques, Jason T.
Guo, Zhongliang
Zhao, Shuai
author_facet Wang, Kaixuan
Diao, Chenxin
Jacques, Jason T.
Guo, Zhongliang
Zhao, Shuai
contents Millions of individuals' well-being are challenged by the harms of substance use. Harm reduction as a public health strategy is designed to improve their health outcomes and reduce safety risks. Some large language models (LLMs) have demonstrated a decent level of medical knowledge, promising to address the information needs of people who use drugs (PWUD). However, their performance in relevant tasks remains largely unexplored. We introduce HRIPBench, a benchmark designed to evaluate LLM's accuracy and safety risks in harm reduction information provision. The benchmark dataset HRIP-Basic has 2,160 question-answer-evidence pairs. The scope covers three tasks: checking safety boundaries, providing quantitative values, and inferring polysubstance use risks. We build the Instruction and RAG schemes to evaluate model behaviours based on their inherent knowledge and the integration of domain knowledge. Our results indicate that state-of-the-art LLMs still struggle to provide accurate harm reduction information, and sometimes, carry out severe safety risks to PWUD. The use of LLMs in harm reduction contexts should be cautiously constrained to avoid inducing negative health outcomes. WARNING: This paper contains illicit content that potentially induces harms.
format Preprint
id arxiv_https___arxiv_org_abs_2507_21815
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle HRIPBench: Benchmarking LLMs in Harm Reduction Information Provision to Support People Who Use Drugs
Wang, Kaixuan
Diao, Chenxin
Jacques, Jason T.
Guo, Zhongliang
Zhao, Shuai
Computation and Language
Computers and Society
Millions of individuals' well-being are challenged by the harms of substance use. Harm reduction as a public health strategy is designed to improve their health outcomes and reduce safety risks. Some large language models (LLMs) have demonstrated a decent level of medical knowledge, promising to address the information needs of people who use drugs (PWUD). However, their performance in relevant tasks remains largely unexplored. We introduce HRIPBench, a benchmark designed to evaluate LLM's accuracy and safety risks in harm reduction information provision. The benchmark dataset HRIP-Basic has 2,160 question-answer-evidence pairs. The scope covers three tasks: checking safety boundaries, providing quantitative values, and inferring polysubstance use risks. We build the Instruction and RAG schemes to evaluate model behaviours based on their inherent knowledge and the integration of domain knowledge. Our results indicate that state-of-the-art LLMs still struggle to provide accurate harm reduction information, and sometimes, carry out severe safety risks to PWUD. The use of LLMs in harm reduction contexts should be cautiously constrained to avoid inducing negative health outcomes. WARNING: This paper contains illicit content that potentially induces harms.
title HRIPBench: Benchmarking LLMs in Harm Reduction Information Provision to Support People Who Use Drugs
topic Computation and Language
Computers and Society
url https://arxiv.org/abs/2507.21815