Towards Interpretable Renal Health Decline Forecasting via Multi-LMM Collaborative Reasoning Framework

Fuente: arXiv
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Hauptverfasser: Wu, Peng-Yi, Huang, Pei-Cing, Chen, Ting-Yu, Ku, Chantung, Lin, Ming-Yen, Kang, Yihuang
Format: Preprint
Veröffentlicht: 2025
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author Wu, Peng-Yi
Huang, Pei-Cing
Chen, Ting-Yu
Ku, Chantung
Lin, Ming-Yen
Kang, Yihuang
author_facet Wu, Peng-Yi
Huang, Pei-Cing
Chen, Ting-Yu
Ku, Chantung
Lin, Ming-Yen
Kang, Yihuang
contents Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown strong potential in clinical prediction tasks due to their ability to process visual and textual information. However, challenges related to deployment cost, data privacy, and model reliability hinder their adoption. In this study, we propose a collaborative framework that enhances the performance of open-source LMMs for eGFR forecasting while generating clinically meaningful explanations. The framework incorporates visual knowledge transfer, abductive reasoning, and a short-term memory mechanism to enhance prediction accuracy and interpretability. Experimental results show that the proposed framework achieves predictive performance and interpretability comparable to proprietary models. It also provides plausible clinical reasoning processes behind each prediction. Our method sheds new light on building AI systems for healthcare that combine predictive accuracy with clinically grounded interpretability.
format Preprint
id arxiv_https___arxiv_org_abs_2507_22464
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Towards Interpretable Renal Health Decline Forecasting via Multi-LMM Collaborative Reasoning Framework
Wu, Peng-Yi
Huang, Pei-Cing
Chen, Ting-Yu
Ku, Chantung
Lin, Ming-Yen
Kang, Yihuang
Machine Learning
Artificial Intelligence
Multiagent Systems
Applications
Accurate and interpretable prediction of estimated glomerular filtration rate (eGFR) is essential for managing chronic kidney disease (CKD) and supporting clinical decisions. Recent advances in Large Multimodal Models (LMMs) have shown strong potential in clinical prediction tasks due to their ability to process visual and textual information. However, challenges related to deployment cost, data privacy, and model reliability hinder their adoption. In this study, we propose a collaborative framework that enhances the performance of open-source LMMs for eGFR forecasting while generating clinically meaningful explanations. The framework incorporates visual knowledge transfer, abductive reasoning, and a short-term memory mechanism to enhance prediction accuracy and interpretability. Experimental results show that the proposed framework achieves predictive performance and interpretability comparable to proprietary models. It also provides plausible clinical reasoning processes behind each prediction. Our method sheds new light on building AI systems for healthcare that combine predictive accuracy with clinically grounded interpretability.
title Towards Interpretable Renal Health Decline Forecasting via Multi-LMM Collaborative Reasoning Framework
topic Machine Learning
Artificial Intelligence
Multiagent Systems
Applications
url https://arxiv.org/abs/2507.22464