Reproducibility and scientific interpretation in the age of AI: consilience in biological systematics, ecology, and molecular biology

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Main Authors: Santos, Charles Morphy D., Paulino, Luciana Campos, Andrade, Michaella P., Tognella-Poccia, Gabriel, Gois, João Paulo
Format: Preprint
Published: 2025
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author Santos, Charles Morphy D.
Paulino, Luciana Campos
Andrade, Michaella P.
Tognella-Poccia, Gabriel
Gois, João Paulo
author_facet Santos, Charles Morphy D.
Paulino, Luciana Campos
Andrade, Michaella P.
Tognella-Poccia, Gabriel
Gois, João Paulo
contents Achieving complete reproducibility in science, particularly in research fields such as biodiversity, is challenging due to analytical choices, bias and interpretation. Here, we examine examples of reproducibility in biological systematics, ecology, and molecular biology. To mitigate the impact of interpretation and analytical choices, Artificial Intelligence (AI) has provided potential tools. In the present work, while emphasizing the need for methodological rigor and transparency, we acknowledge the role of interpretation in activities such as coding biological characters and detecting morphological patterns in nature. We explore the opportunities and limitations associated with the synergy between big data and AI in molecular biology, emphasizing the need for a more comprehensive and integrated approach based on dataset quality and usefulness. We conclude by advocating for AI-based tools to assist biologists, reinforcing consilience as a criterion for scientific validity without hindering scientific progress.
format Preprint
id arxiv_https___arxiv_org_abs_2507_22942
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Reproducibility and scientific interpretation in the age of AI: consilience in biological systematics, ecology, and molecular biology
Santos, Charles Morphy D.
Paulino, Luciana Campos
Andrade, Michaella P.
Tognella-Poccia, Gabriel
Gois, João Paulo
Other Quantitative Biology
Achieving complete reproducibility in science, particularly in research fields such as biodiversity, is challenging due to analytical choices, bias and interpretation. Here, we examine examples of reproducibility in biological systematics, ecology, and molecular biology. To mitigate the impact of interpretation and analytical choices, Artificial Intelligence (AI) has provided potential tools. In the present work, while emphasizing the need for methodological rigor and transparency, we acknowledge the role of interpretation in activities such as coding biological characters and detecting morphological patterns in nature. We explore the opportunities and limitations associated with the synergy between big data and AI in molecular biology, emphasizing the need for a more comprehensive and integrated approach based on dataset quality and usefulness. We conclude by advocating for AI-based tools to assist biologists, reinforcing consilience as a criterion for scientific validity without hindering scientific progress.
title Reproducibility and scientific interpretation in the age of AI: consilience in biological systematics, ecology, and molecular biology
topic Other Quantitative Biology
url https://arxiv.org/abs/2507.22942