On the Risk of Misleading Reports: Diagnosing Textual Biases in Multimodal Clinical AI

Fuente: arXiv
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Autori principali: Restrepo, David, Ktena, Ira, Vakalopoulou, Maria, Christodoulidis, Stergios, Ferrante, Enzo
Natura: Preprint
Pubblicazione: 2025
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author Restrepo, David
Ktena, Ira
Vakalopoulou, Maria
Christodoulidis, Stergios
Ferrante, Enzo
author_facet Restrepo, David
Ktena, Ira
Vakalopoulou, Maria
Christodoulidis, Stergios
Ferrante, Enzo
contents Clinical decision-making relies on the integrated analysis of medical images and the associated clinical reports. While Vision-Language Models (VLMs) can offer a unified framework for such tasks, they can exhibit strong biases toward one modality, frequently overlooking critical visual cues in favor of textual information. In this work, we introduce Selective Modality Shifting (SMS), a perturbation-based approach to quantify a model's reliance on each modality in binary classification tasks. By systematically swapping images or text between samples with opposing labels, we expose modality-specific biases. We assess six open-source VLMs-four generalist models and two fine-tuned for medical data-on two medical imaging datasets with distinct modalities: MIMIC-CXR (chest X-ray) and FairVLMed (scanning laser ophthalmoscopy). By assessing model performance and the calibration of every model in both unperturbed and perturbed settings, we reveal a marked dependency on text input, which persists despite the presence of complementary visual information. We also perform a qualitative attention-based analysis which further confirms that image content is often overshadowed by text details. Our findings highlight the importance of designing and evaluating multimodal medical models that genuinely integrate visual and textual cues, rather than relying on single-modality signals.
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id arxiv_https___arxiv_org_abs_2508_00171
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle On the Risk of Misleading Reports: Diagnosing Textual Biases in Multimodal Clinical AI
Restrepo, David
Ktena, Ira
Vakalopoulou, Maria
Christodoulidis, Stergios
Ferrante, Enzo
Computer Vision and Pattern Recognition
Computation and Language
Clinical decision-making relies on the integrated analysis of medical images and the associated clinical reports. While Vision-Language Models (VLMs) can offer a unified framework for such tasks, they can exhibit strong biases toward one modality, frequently overlooking critical visual cues in favor of textual information. In this work, we introduce Selective Modality Shifting (SMS), a perturbation-based approach to quantify a model's reliance on each modality in binary classification tasks. By systematically swapping images or text between samples with opposing labels, we expose modality-specific biases. We assess six open-source VLMs-four generalist models and two fine-tuned for medical data-on two medical imaging datasets with distinct modalities: MIMIC-CXR (chest X-ray) and FairVLMed (scanning laser ophthalmoscopy). By assessing model performance and the calibration of every model in both unperturbed and perturbed settings, we reveal a marked dependency on text input, which persists despite the presence of complementary visual information. We also perform a qualitative attention-based analysis which further confirms that image content is often overshadowed by text details. Our findings highlight the importance of designing and evaluating multimodal medical models that genuinely integrate visual and textual cues, rather than relying on single-modality signals.
title On the Risk of Misleading Reports: Diagnosing Textual Biases in Multimodal Clinical AI
topic Computer Vision and Pattern Recognition
Computation and Language
url https://arxiv.org/abs/2508.00171