Weakly Supervised Intracranial Aneurysm Detection and Segmentation in MR angiography via Multi-task UNet with Vesselness Prior

Fuente: arXiv
Guardado en:
Detalles Bibliográficos
Autores principales: Rainville, Erin, Rasoulian, Amirhossein, Rivaz, Hassan, Xiao, Yiming
Formato: Preprint
Publicado: 2025
Materias:
Acceso en línea:
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
_version_ 1866912514805071872
author Rainville, Erin
Rasoulian, Amirhossein
Rivaz, Hassan
Xiao, Yiming
author_facet Rainville, Erin
Rasoulian, Amirhossein
Rivaz, Hassan
Xiao, Yiming
contents Intracranial aneurysms (IAs) are abnormal dilations of cerebral blood vessels that, if ruptured, can lead to life-threatening consequences. However, their small size and soft contrast in radiological scans often make it difficult to perform accurate and efficient detection and morphological analyses, which are critical in the clinical care of the disorder. Furthermore, the lack of large public datasets with voxel-wise expert annotations pose challenges for developing deep learning algorithms to address the issues. Therefore, we proposed a novel weakly supervised 3D multi-task UNet that integrates vesselness priors to jointly perform aneurysm detection and segmentation in time-of-flight MR angiography (TOF-MRA). Specifically, to robustly guide IA detection and segmentation, we employ the popular Frangi's vesselness filter to derive soft cerebrovascular priors for both network input and an attention block to conduct segmentation from the decoder and detection from an auxiliary branch. We train our model on the Lausanne dataset with coarse ground truth segmentation, and evaluate it on the test set with refined labels from the same database. To further assess our model's generalizability, we also validate it externally on the ADAM dataset. Our results demonstrate the superior performance of the proposed technique over the SOTA techniques for aneurysm segmentation (Dice = 0.614, 95%HD =1.38mm) and detection (false positive rate = 1.47, sensitivity = 92.9%).
format Preprint
id arxiv_https___arxiv_org_abs_2508_00235
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Weakly Supervised Intracranial Aneurysm Detection and Segmentation in MR angiography via Multi-task UNet with Vesselness Prior
Rainville, Erin
Rasoulian, Amirhossein
Rivaz, Hassan
Xiao, Yiming
Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
Intracranial aneurysms (IAs) are abnormal dilations of cerebral blood vessels that, if ruptured, can lead to life-threatening consequences. However, their small size and soft contrast in radiological scans often make it difficult to perform accurate and efficient detection and morphological analyses, which are critical in the clinical care of the disorder. Furthermore, the lack of large public datasets with voxel-wise expert annotations pose challenges for developing deep learning algorithms to address the issues. Therefore, we proposed a novel weakly supervised 3D multi-task UNet that integrates vesselness priors to jointly perform aneurysm detection and segmentation in time-of-flight MR angiography (TOF-MRA). Specifically, to robustly guide IA detection and segmentation, we employ the popular Frangi's vesselness filter to derive soft cerebrovascular priors for both network input and an attention block to conduct segmentation from the decoder and detection from an auxiliary branch. We train our model on the Lausanne dataset with coarse ground truth segmentation, and evaluate it on the test set with refined labels from the same database. To further assess our model's generalizability, we also validate it externally on the ADAM dataset. Our results demonstrate the superior performance of the proposed technique over the SOTA techniques for aneurysm segmentation (Dice = 0.614, 95%HD =1.38mm) and detection (false positive rate = 1.47, sensitivity = 92.9%).
title Weakly Supervised Intracranial Aneurysm Detection and Segmentation in MR angiography via Multi-task UNet with Vesselness Prior
topic Image and Video Processing
Artificial Intelligence
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2508.00235