Structured Spectral Graph Learning for Anomaly Classification in 3D Chest CT Scans

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Main Authors: Di Piazza, Theo, Lazarus, Carole, Nempont, Olivier, Boussel, Loic
Format: Preprint
Published: 2025
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author Di Piazza, Theo
Lazarus, Carole
Nempont, Olivier
Boussel, Loic
author_facet Di Piazza, Theo
Lazarus, Carole
Nempont, Olivier
Boussel, Loic
contents With the increasing number of CT scan examinations, there is a need for automated methods such as organ segmentation, anomaly detection and report generation to assist radiologists in managing their increasing workload. Multi-label classification of 3D CT scans remains a critical yet challenging task due to the complex spatial relationships within volumetric data and the variety of observed anomalies. Existing approaches based on 3D convolutional networks have limited abilities to model long-range dependencies while Vision Transformers suffer from high computational costs and often require extensive pre-training on large-scale datasets from the same domain to achieve competitive performance. In this work, we propose an alternative by introducing a new graph-based approach that models CT scans as structured graphs, leveraging axial slice triplets nodes processed through spectral domain convolution to enhance multi-label anomaly classification performance. Our method exhibits strong cross-dataset generalization, and competitive performance while achieving robustness to z-axis translation. An ablation study evaluates the contribution of each proposed component.
format Preprint
id arxiv_https___arxiv_org_abs_2508_01045
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Structured Spectral Graph Learning for Anomaly Classification in 3D Chest CT Scans
Di Piazza, Theo
Lazarus, Carole
Nempont, Olivier
Boussel, Loic
Computer Vision and Pattern Recognition
Machine Learning
With the increasing number of CT scan examinations, there is a need for automated methods such as organ segmentation, anomaly detection and report generation to assist radiologists in managing their increasing workload. Multi-label classification of 3D CT scans remains a critical yet challenging task due to the complex spatial relationships within volumetric data and the variety of observed anomalies. Existing approaches based on 3D convolutional networks have limited abilities to model long-range dependencies while Vision Transformers suffer from high computational costs and often require extensive pre-training on large-scale datasets from the same domain to achieve competitive performance. In this work, we propose an alternative by introducing a new graph-based approach that models CT scans as structured graphs, leveraging axial slice triplets nodes processed through spectral domain convolution to enhance multi-label anomaly classification performance. Our method exhibits strong cross-dataset generalization, and competitive performance while achieving robustness to z-axis translation. An ablation study evaluates the contribution of each proposed component.
title Structured Spectral Graph Learning for Anomaly Classification in 3D Chest CT Scans
topic Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2508.01045