A computational fluid dynamics model for the simulation of flashboiling flow inside pressurized metered dose inhalers
Fuente:
arXiv
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | Preprint |
| Publicado: |
2025
|
| Materias: | |
| Acceso en línea: | |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| _version_ | 1866912524735086592 |
|---|---|
| author | Rossi, Riccardo Cottini, Ciro Benassi, Andrea |
| author_facet | Rossi, Riccardo Cottini, Ciro Benassi, Andrea |
| contents | In this work we present, for the first time, a computational fluid dynamics tool for the simulation of the metered discharge in a pressurized metered dose inhaler. The model, based on open-source software, adopts the Volume-Of-Fluid method for the representation of the multiphase flow inside the device and a cavitation model to explicitly account for the onset of flashboiling upon actuation. Experimental visualizations of the flow inside the device and measurements of the mixture density and liquid and vapor flow rates at the nozzle orifice are employed to validate the model and assess the sensitivity of numerical results to modeling parameters. The results obtained for a standard device geometry show that the model is able to quantitatively predict several aspects of the dynamics and thermodynamics of the metered discharge. We conclude by showing how, by allowing to reproduce and understand the fluid dynamics upstream of the atomizing nozzle, our computational tool enables systematic design and optimization of the actuator geometry. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2508_02316 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | A computational fluid dynamics model for the simulation of flashboiling flow inside pressurized metered dose inhalers Rossi, Riccardo Cottini, Ciro Benassi, Andrea Fluid Dynamics In this work we present, for the first time, a computational fluid dynamics tool for the simulation of the metered discharge in a pressurized metered dose inhaler. The model, based on open-source software, adopts the Volume-Of-Fluid method for the representation of the multiphase flow inside the device and a cavitation model to explicitly account for the onset of flashboiling upon actuation. Experimental visualizations of the flow inside the device and measurements of the mixture density and liquid and vapor flow rates at the nozzle orifice are employed to validate the model and assess the sensitivity of numerical results to modeling parameters. The results obtained for a standard device geometry show that the model is able to quantitatively predict several aspects of the dynamics and thermodynamics of the metered discharge. We conclude by showing how, by allowing to reproduce and understand the fluid dynamics upstream of the atomizing nozzle, our computational tool enables systematic design and optimization of the actuator geometry. |
| title | A computational fluid dynamics model for the simulation of flashboiling flow inside pressurized metered dose inhalers |
| topic | Fluid Dynamics |
| url | https://arxiv.org/abs/2508.02316 |