Clinically Grounded Agent-based Report Evaluation: An Interpretable Metric for Radiology Report Generation

Fuente: arXiv
Guardado en:
Detalles Bibliográficos
Autores principales: Dua, Radhika, Joon, Young, Kwon, Dogra, Siddhant, Freedman, Daniel, Ruan, Diana, Nashawaty, Motaz, Rigau, Danielle, Alber, Daniel Alexander, Zhang, Kang, Cho, Kyunghyun, Oermann, Eric Karl
Formato: Preprint
Publicado: 2025
Materias:
Acceso en línea:
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
_version_ 1866909721807552512
author Dua, Radhika
Joon, Young
Kwon
Dogra, Siddhant
Freedman, Daniel
Ruan, Diana
Nashawaty, Motaz
Rigau, Danielle
Alber, Daniel Alexander
Zhang, Kang
Cho, Kyunghyun
Oermann, Eric Karl
author_facet Dua, Radhika
Joon, Young
Kwon
Dogra, Siddhant
Freedman, Daniel
Ruan, Diana
Nashawaty, Motaz
Rigau, Danielle
Alber, Daniel Alexander
Zhang, Kang
Cho, Kyunghyun
Oermann, Eric Karl
contents Radiological imaging is central to diagnosis, treatment planning, and clinical decision-making. Vision-language foundation models have spurred interest in automated radiology report generation (RRG), but safe deployment requires reliable clinical evaluation of generated reports. Existing metrics often rely on surface-level similarity or behave as black boxes, lacking interpretability. We introduce ICARE (Interpretable and Clinically-grounded Agent-based Report Evaluation), an interpretable evaluation framework leveraging large language model agents and dynamic multiple-choice question answering (MCQA). Two agents, each with either the ground-truth or generated report, generate clinically meaningful questions and quiz each other. Agreement on answers captures preservation and consistency of findings, serving as interpretable proxies for clinical precision and recall. By linking scores to question-answer pairs, ICARE enables transparent, and interpretable assessment. Clinician studies show ICARE aligns significantly more with expert judgment than prior metrics. Perturbation analyses confirm sensitivity to clinical content and reproducibility, while model comparisons reveal interpretable error patterns.
format Preprint
id arxiv_https___arxiv_org_abs_2508_02808
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Clinically Grounded Agent-based Report Evaluation: An Interpretable Metric for Radiology Report Generation
Dua, Radhika
Joon, Young
Kwon
Dogra, Siddhant
Freedman, Daniel
Ruan, Diana
Nashawaty, Motaz
Rigau, Danielle
Alber, Daniel Alexander
Zhang, Kang
Cho, Kyunghyun
Oermann, Eric Karl
Computation and Language
Artificial Intelligence
Machine Learning
Radiological imaging is central to diagnosis, treatment planning, and clinical decision-making. Vision-language foundation models have spurred interest in automated radiology report generation (RRG), but safe deployment requires reliable clinical evaluation of generated reports. Existing metrics often rely on surface-level similarity or behave as black boxes, lacking interpretability. We introduce ICARE (Interpretable and Clinically-grounded Agent-based Report Evaluation), an interpretable evaluation framework leveraging large language model agents and dynamic multiple-choice question answering (MCQA). Two agents, each with either the ground-truth or generated report, generate clinically meaningful questions and quiz each other. Agreement on answers captures preservation and consistency of findings, serving as interpretable proxies for clinical precision and recall. By linking scores to question-answer pairs, ICARE enables transparent, and interpretable assessment. Clinician studies show ICARE aligns significantly more with expert judgment than prior metrics. Perturbation analyses confirm sensitivity to clinical content and reproducibility, while model comparisons reveal interpretable error patterns.
title Clinically Grounded Agent-based Report Evaluation: An Interpretable Metric for Radiology Report Generation
topic Computation and Language
Artificial Intelligence
Machine Learning
url https://arxiv.org/abs/2508.02808