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Main Authors: Yi, Ziruo, Liu, Jinyu, Xiao, Ting, Albert, Mark V.
Format: Preprint
Published: 2025
Subjects:
Online Access:https://arxiv.org/abs/2508.02841
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author Yi, Ziruo
Liu, Jinyu
Xiao, Ting
Albert, Mark V.
author_facet Yi, Ziruo
Liu, Jinyu
Xiao, Ting
Albert, Mark V.
contents Radiology visual question answering (RVQA) provides precise answers to questions about chest X-ray images, alleviating radiologists' workload. While recent methods based on multimodal large language models (MLLMs) and retrieval-augmented generation (RAG) have shown promising progress in RVQA, they still face challenges in factual accuracy, hallucinations, and cross-modal misalignment. We introduce a multi-agent system (MAS) designed to support complex reasoning in RVQA, with specialized agents for context understanding, multimodal reasoning, and answer validation. We evaluate our system on a challenging RVQA set curated via model disagreement filtering, comprising consistently hard cases across multiple MLLMs. Extensive experiments demonstrate the superiority and effectiveness of our system over strong MLLM baselines, with a case study illustrating its reliability and interpretability. This work highlights the potential of multi-agent approaches to support explainable and trustworthy clinical AI applications that require complex reasoning.
format Preprint
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institution arXiv
publishDate 2025
record_format arxiv
spellingShingle A Multi-Agent System for Complex Reasoning in Radiology Visual Question Answering
Yi, Ziruo
Liu, Jinyu
Xiao, Ting
Albert, Mark V.
Artificial Intelligence
Information Retrieval
Radiology visual question answering (RVQA) provides precise answers to questions about chest X-ray images, alleviating radiologists' workload. While recent methods based on multimodal large language models (MLLMs) and retrieval-augmented generation (RAG) have shown promising progress in RVQA, they still face challenges in factual accuracy, hallucinations, and cross-modal misalignment. We introduce a multi-agent system (MAS) designed to support complex reasoning in RVQA, with specialized agents for context understanding, multimodal reasoning, and answer validation. We evaluate our system on a challenging RVQA set curated via model disagreement filtering, comprising consistently hard cases across multiple MLLMs. Extensive experiments demonstrate the superiority and effectiveness of our system over strong MLLM baselines, with a case study illustrating its reliability and interpretability. This work highlights the potential of multi-agent approaches to support explainable and trustworthy clinical AI applications that require complex reasoning.
title A Multi-Agent System for Complex Reasoning in Radiology Visual Question Answering
topic Artificial Intelligence
Information Retrieval
url https://arxiv.org/abs/2508.02841