RefineSeg: Dual Coarse-to-Fine Learning for Medical Image Segmentation

Fuente: arXiv
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Main Authors: Du, Anghong, Aung, Nay, Arvanitis, Theodoros N., Piechnik, Stefan K., Lima, Joao A C, Petersen, Steffen E., Zhang, Le
Format: Preprint
Published: 2025
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author Du, Anghong
Aung, Nay
Arvanitis, Theodoros N.
Piechnik, Stefan K.
Lima, Joao A C
Petersen, Steffen E.
Zhang, Le
author_facet Du, Anghong
Aung, Nay
Arvanitis, Theodoros N.
Piechnik, Stefan K.
Lima, Joao A C
Petersen, Steffen E.
Zhang, Le
contents High-quality pixel-level annotations of medical images are essential for supervised segmentation tasks, but obtaining such annotations is costly and requires medical expertise. To address this challenge, we propose a novel coarse-to-fine segmentation framework that relies entirely on coarse-level annotations, encompassing both target and complementary drawings, despite their inherent noise. The framework works by introducing transition matrices in order to model the inaccurate and incomplete regions in the coarse annotations. By jointly training on multiple sets of coarse annotations, it progressively refines the network's outputs and infers the true segmentation distribution, achieving a robust approximation of precise labels through matrix-based modeling. To validate the flexibility and effectiveness of the proposed method, we demonstrate the results on two public cardiac imaging datasets, ACDC and MSCMRseg, and further evaluate its performance on the UK Biobank dataset. Experimental results indicate that our approach surpasses the state-of-the-art weakly supervised methods and closely matches the fully supervised approach.
format Preprint
id arxiv_https___arxiv_org_abs_2508_02844
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle RefineSeg: Dual Coarse-to-Fine Learning for Medical Image Segmentation
Du, Anghong
Aung, Nay
Arvanitis, Theodoros N.
Piechnik, Stefan K.
Lima, Joao A C
Petersen, Steffen E.
Zhang, Le
Computer Vision and Pattern Recognition
High-quality pixel-level annotations of medical images are essential for supervised segmentation tasks, but obtaining such annotations is costly and requires medical expertise. To address this challenge, we propose a novel coarse-to-fine segmentation framework that relies entirely on coarse-level annotations, encompassing both target and complementary drawings, despite their inherent noise. The framework works by introducing transition matrices in order to model the inaccurate and incomplete regions in the coarse annotations. By jointly training on multiple sets of coarse annotations, it progressively refines the network's outputs and infers the true segmentation distribution, achieving a robust approximation of precise labels through matrix-based modeling. To validate the flexibility and effectiveness of the proposed method, we demonstrate the results on two public cardiac imaging datasets, ACDC and MSCMRseg, and further evaluate its performance on the UK Biobank dataset. Experimental results indicate that our approach surpasses the state-of-the-art weakly supervised methods and closely matches the fully supervised approach.
title RefineSeg: Dual Coarse-to-Fine Learning for Medical Image Segmentation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2508.02844