Nexus-INR: Diverse Knowledge-guided Arbitrary-Scale Multimodal Medical Image Super-Resolution

Fuente: arXiv
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Auteurs principaux: Zhang, Bo, Huo, JianFei, Zhang, Zheng, Wang, Wufan, Gao, Hui, Gong, Xiangyang, Wang, Wendong
Format: Preprint
Publié: 2025
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author Zhang, Bo
Huo, JianFei
Zhang, Zheng
Wang, Wufan
Gao, Hui
Gong, Xiangyang
Wang, Wendong
author_facet Zhang, Bo
Huo, JianFei
Zhang, Zheng
Wang, Wufan
Gao, Hui
Gong, Xiangyang
Wang, Wendong
contents Arbitrary-resolution super-resolution (ARSR) provides crucial flexibility for medical image analysis by adapting to diverse spatial resolutions. However, traditional CNN-based methods are inherently ill-suited for ARSR, as they are typically designed for fixed upsampling factors. While INR-based methods overcome this limitation, they still struggle to effectively process and leverage multi-modal images with varying resolutions and details. In this paper, we propose Nexus-INR, a Diverse Knowledge-guided ARSR framework, which employs varied information and downstream tasks to achieve high-quality, adaptive-resolution medical image super-resolution. Specifically, Nexus-INR contains three key components. A dual-branch encoder with an auxiliary classification task to effectively disentangle shared anatomical structures and modality-specific features; a knowledge distillation module using cross-modal attention that guides low-resolution modality reconstruction with high-resolution reference, enhanced by self-supervised consistency loss; an integrated segmentation module that embeds anatomical semantics to improve both reconstruction quality and downstream segmentation performance. Experiments on the BraTS2020 dataset for both super-resolution and downstream segmentation demonstrate that Nexus-INR outperforms state-of-the-art methods across various metrics.
format Preprint
id arxiv_https___arxiv_org_abs_2508_03073
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Nexus-INR: Diverse Knowledge-guided Arbitrary-Scale Multimodal Medical Image Super-Resolution
Zhang, Bo
Huo, JianFei
Zhang, Zheng
Wang, Wufan
Gao, Hui
Gong, Xiangyang
Wang, Wendong
Image and Video Processing
Computer Vision and Pattern Recognition
Arbitrary-resolution super-resolution (ARSR) provides crucial flexibility for medical image analysis by adapting to diverse spatial resolutions. However, traditional CNN-based methods are inherently ill-suited for ARSR, as they are typically designed for fixed upsampling factors. While INR-based methods overcome this limitation, they still struggle to effectively process and leverage multi-modal images with varying resolutions and details. In this paper, we propose Nexus-INR, a Diverse Knowledge-guided ARSR framework, which employs varied information and downstream tasks to achieve high-quality, adaptive-resolution medical image super-resolution. Specifically, Nexus-INR contains three key components. A dual-branch encoder with an auxiliary classification task to effectively disentangle shared anatomical structures and modality-specific features; a knowledge distillation module using cross-modal attention that guides low-resolution modality reconstruction with high-resolution reference, enhanced by self-supervised consistency loss; an integrated segmentation module that embeds anatomical semantics to improve both reconstruction quality and downstream segmentation performance. Experiments on the BraTS2020 dataset for both super-resolution and downstream segmentation demonstrate that Nexus-INR outperforms state-of-the-art methods across various metrics.
title Nexus-INR: Diverse Knowledge-guided Arbitrary-Scale Multimodal Medical Image Super-Resolution
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2508.03073