The benefit of dose-exposure-response modeling in the estimation of dose-response relationship and dose optimization: some theoretical and simulation evidence
Fuente:
arXiv
Saved in:
| Main Authors: | Wang, Jixian, Zhang, Zhiwei, Tiwari, Ram |
|---|---|
| Format: | Preprint |
| Published: |
2025
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
Robust estimation of causal dose-response relationship using exposure data with dose as an instrumental variable
by: Wang, Jixian, et al.
Published: (2025)
by: Wang, Jixian, et al.
Published: (2025)
A longitudinal Bayesian framework for estimating causal dose-response relationships
by: Luo, Yu, et al.
Published: (2025)
by: Luo, Yu, et al.
Published: (2025)
Fast convergence rates for dose-response estimation
by: Bonvini, Matteo, et al.
Published: (2022)
by: Bonvini, Matteo, et al.
Published: (2022)
A Bayesian Bootstrap Approach for Dynamic Borrowing for Minimizing Mean Squared Error
by: Wang, Jixian, et al.
Published: (2024)
by: Wang, Jixian, et al.
Published: (2024)
Estimation of causal dose-response functions under data fusion
by: Lim, Jaewon, et al.
Published: (2025)
by: Lim, Jaewon, et al.
Published: (2025)
Testing for similarity of dose response in multi-regional clinical trials
by: Dette, Holger, et al.
Published: (2024)
by: Dette, Holger, et al.
Published: (2024)
Balancing the effective sample size in prior across different doses in the curve-free Bayesian decision-theoretic design for dose-finding trials
by: Xu, Jiapeng, et al.
Published: (2025)
by: Xu, Jiapeng, et al.
Published: (2025)
A Bayesian design for dual-agent dose optimization with targeted therapies
by: Jiménez, José L., et al.
Published: (2022)
by: Jiménez, José L., et al.
Published: (2022)
Using representation balancing to learn conditional-average dose responses from clustered data
by: Bockel-Rickermann, Christopher, et al.
Published: (2023)
by: Bockel-Rickermann, Christopher, et al.
Published: (2023)
Potential outcome simulation for efficient head-to-head comparison of adaptive dose-finding designs
by: Sweeting, Michael, et al.
Published: (2024)
by: Sweeting, Michael, et al.
Published: (2024)
BARD: A seamless two-stage dose optimization design integrating backfill and adaptive randomization
by: Zhao, Yixuan, et al.
Published: (2024)
by: Zhao, Yixuan, et al.
Published: (2024)
Using joint models in phase I dose-finding designs in oncology: considerations for frequentist approaches
by: Chen, Xijin, et al.
Published: (2025)
by: Chen, Xijin, et al.
Published: (2025)
Optimal designs for identifying effective doses in drug combination studies
by: Schürmeyer, Leonie, et al.
Published: (2025)
by: Schürmeyer, Leonie, et al.
Published: (2025)
Estimating risk factors for pathogenic dose accrual from longitudinal data
by: Sewell, Daniel K., et al.
Published: (2024)
by: Sewell, Daniel K., et al.
Published: (2024)
Two-dose vs. Three-Dose Optimization Under Sample Size Constraint
by: Sun, Linda, et al.
Published: (2026)
by: Sun, Linda, et al.
Published: (2026)
A Bayesian model-free dose-finding approach in Phase II clinical trials with the flexibility of historical borrowing
by: Han, Linxi, et al.
Published: (2025)
by: Han, Linxi, et al.
Published: (2025)
U-DESPE: a Bayesian Utility-based methodology for dosing regimen optimization in early-phase oncology trials based on Dose-Exposure, Safety, Pharmacodynamics, Efficacy
by: Andrillon, Anaïs, et al.
Published: (2025)
by: Andrillon, Anaïs, et al.
Published: (2025)
Evaluating marginal likelihood approximations of dose-response relationship models in Bayesian benchmark dose methods for risk assessment
by: Minewaki, Sota, et al.
Published: (2024)
by: Minewaki, Sota, et al.
Published: (2024)
TITE-CLRM: Towards efficient time-to-event dose-escalation guidance of multi-cycle cancer therapies
by: Widmer, Lukas Andreas, et al.
Published: (2024)
by: Widmer, Lukas Andreas, et al.
Published: (2024)
Simultaneous dose and dose rate optimization via dose modifying factor modeling for FLASH effective dose
by: Jiangjun Ma, et al.
Published: (2024)
by: Jiangjun Ma, et al.
Published: (2024)
Causal exposure-response curve estimation with surrogate confounders: a study of air pollution and children's health in Medicaid claims data
by: Lee, Jenny J., et al.
Published: (2023)
by: Lee, Jenny J., et al.
Published: (2023)
Benchmark dose modeling for epidemiological dose–response assessment using case‐control studies
by: Francesco De Pretis, et al.
Published: (2024)
by: Francesco De Pretis, et al.
Published: (2024)
Nonparametric assessment of regimen response curve estimators
by: Pham, Cuong, et al.
Published: (2024)
by: Pham, Cuong, et al.
Published: (2024)
A mixture of distributed lag non-linear models to account for spatially heterogeneous exposure-lag-response associations
by: Briz-Redón, Álvaro, et al.
Published: (2025)
by: Briz-Redón, Álvaro, et al.
Published: (2025)
Prenatal alcohol exposure and child cognition: semi-continuous exposures, causal inference and evidence synthesis
by: Wang, Xiaoya, et al.
Published: (2025)
by: Wang, Xiaoya, et al.
Published: (2025)
Subgroup analysis in multi level hierarchical cluster randomized trials
by: Chakraborty, Shubhadeep, et al.
Published: (2024)
by: Chakraborty, Shubhadeep, et al.
Published: (2024)
Towards an adequate description of the dose‐response relationship in BNCT of glioblastoma multiforme
by: Barbara Marcaccio, et al.
Published: (2025)
by: Barbara Marcaccio, et al.
Published: (2025)
A dose–response analysis of the effects of prenatal alcohol exposure on cognitive development
by: Joseph L. Jacobson, et al.
Published: (2024)
by: Joseph L. Jacobson, et al.
Published: (2024)
An adaptive design for optimizing treatment assignment in randomized clinical trials
by: Zhang, Wei, et al.
Published: (2025)
by: Zhang, Wei, et al.
Published: (2025)
Item response parameter estimation performance using Gaussian quadrature and Laplace
by: Arrington, Leticia, et al.
Published: (2024)
by: Arrington, Leticia, et al.
Published: (2024)
Factor tree copula models for item response data
by: Kadhem, Sayed H., et al.
Published: (2022)
by: Kadhem, Sayed H., et al.
Published: (2022)
Large multi-response linear regression estimation based on low-rank pre-smoothing
by: Tian, Xinle, et al.
Published: (2024)
by: Tian, Xinle, et al.
Published: (2024)
Learning by exporting with a dose-response function
by: Micocci, Francesca, et al.
Published: (2025)
by: Micocci, Francesca, et al.
Published: (2025)
A nutritionally informed model for Bayesian variable selection with metabolite response variables
by: Clark-Boucher, Dylan, et al.
Published: (2025)
by: Clark-Boucher, Dylan, et al.
Published: (2025)
How many federal employees are not satisfied? Using response times to estimate population proportions under the survey variable cause model
by: Auerbach, Jonathan
Published: (2025)
by: Auerbach, Jonathan
Published: (2025)
Asymmetric Laplace distribution regression model for fitting heterogeneous longitudinal response
by: Barbieri, Antoine, et al.
Published: (2025)
by: Barbieri, Antoine, et al.
Published: (2025)
General linear hypothesis testing in ill-conditioned functional response model
by: Smaga, Łukasz, et al.
Published: (2024)
by: Smaga, Łukasz, et al.
Published: (2024)
Omitted covariates bias and finite mixtures of regression models for longitudinal responses
by: Alfo', Marco, et al.
Published: (2026)
by: Alfo', Marco, et al.
Published: (2026)
Approximate Bayesian Analysis for Borrowing External Controls for Randomized Controlled Trials With Dynamic Borrowing and Covariate Balancing Adjustment
by: Jixian Wang, et al.
Published: (2025)
by: Jixian Wang, et al.
Published: (2025)
Statistical evaluation of measurement precision in linear dose-response relationships via interlaboratory studies
by: Takeshita, Jun-ichi, et al.
Published: (2026)
by: Takeshita, Jun-ichi, et al.
Published: (2026)
Similar Items
-
Robust estimation of causal dose-response relationship using exposure data with dose as an instrumental variable
by: Wang, Jixian, et al.
Published: (2025) -
A longitudinal Bayesian framework for estimating causal dose-response relationships
by: Luo, Yu, et al.
Published: (2025) -
Fast convergence rates for dose-response estimation
by: Bonvini, Matteo, et al.
Published: (2022) -
A Bayesian Bootstrap Approach for Dynamic Borrowing for Minimizing Mean Squared Error
by: Wang, Jixian, et al.
Published: (2024) -
Estimation of causal dose-response functions under data fusion
by: Lim, Jaewon, et al.
Published: (2025)