Identifiability of Large Phylogenetic Mixtures for Many Phylogenetic Model Structures

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Hauptverfasser: Kagy, Bryson, Sullivant, Seth
Format: Preprint
Veröffentlicht: 2025
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author Kagy, Bryson
Sullivant, Seth
author_facet Kagy, Bryson
Sullivant, Seth
contents Identifiability of phylogenetic models is a necessary condition to ensure that the model parameters can be uniquely determined from data. Mixture models are phylogenetic models where the probability distributions in the model are convex combinations of distributions in simpler phylogenetic models. Mixture models are used to model heterogeneity in the substitution process in DNA sequences. While many basic phylogenetic models are known to be identifiable, mixture models in generality have only been shown to be identifiable in certain cases. We expand the main theorem of [Rhodes, Sullivant 2012] to prove identifiability of mixture models in equivariant phylogenetic models, specifically the Jukes-Cantor, Kimura 2-parameter model, Kimura 3-parameter model and the Strand Symmetric model.
format Preprint
id arxiv_https___arxiv_org_abs_2508_05832
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle Identifiability of Large Phylogenetic Mixtures for Many Phylogenetic Model Structures
Kagy, Bryson
Sullivant, Seth
Populations and Evolution
Algebraic Geometry
Combinatorics
Statistics Theory
Identifiability of phylogenetic models is a necessary condition to ensure that the model parameters can be uniquely determined from data. Mixture models are phylogenetic models where the probability distributions in the model are convex combinations of distributions in simpler phylogenetic models. Mixture models are used to model heterogeneity in the substitution process in DNA sequences. While many basic phylogenetic models are known to be identifiable, mixture models in generality have only been shown to be identifiable in certain cases. We expand the main theorem of [Rhodes, Sullivant 2012] to prove identifiability of mixture models in equivariant phylogenetic models, specifically the Jukes-Cantor, Kimura 2-parameter model, Kimura 3-parameter model and the Strand Symmetric model.
title Identifiability of Large Phylogenetic Mixtures for Many Phylogenetic Model Structures
topic Populations and Evolution
Algebraic Geometry
Combinatorics
Statistics Theory
url https://arxiv.org/abs/2508.05832