Optical Measurement of Mass Density of Biological Samples
Fuente:
arXiv
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| Autori principali: | , , , , |
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| Natura: | Preprint |
| Pubblicazione: |
2025
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| Soggetti: | |
| Accesso online: | |
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| _version_ | 1866916891158642688 |
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| author | Möckel, Conrad Li, Jiarui Zanini, Giulia Guck, Jochen Scarcelli, Giuliano |
| author_facet | Möckel, Conrad Li, Jiarui Zanini, Giulia Guck, Jochen Scarcelli, Giuliano |
| contents | Mass density is a vital property for improved biophysical understanding of and within biological samples. It is increasingly attracting active investigation, but still lacks reliable, non-contact techniques to accurately characterize it in biological systems. Contrary to popular belief, refractive index information alone is insufficient to determine a sample's mass density, as we demonstrate here theoretically and experimentally. Instead, we measured the nonlinear gain of stimulated Brillouin scattering to provide additional information for mass density estimation. This all-optical method reduces the estimation error tenfold, offering a more accurate and universal technique for mass density measurements. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2508_07899 |
| institution | arXiv |
| publishDate | 2025 |
| record_format | arxiv |
| spellingShingle | Optical Measurement of Mass Density of Biological Samples Möckel, Conrad Li, Jiarui Zanini, Giulia Guck, Jochen Scarcelli, Giuliano Soft Condensed Matter Mass density is a vital property for improved biophysical understanding of and within biological samples. It is increasingly attracting active investigation, but still lacks reliable, non-contact techniques to accurately characterize it in biological systems. Contrary to popular belief, refractive index information alone is insufficient to determine a sample's mass density, as we demonstrate here theoretically and experimentally. Instead, we measured the nonlinear gain of stimulated Brillouin scattering to provide additional information for mass density estimation. This all-optical method reduces the estimation error tenfold, offering a more accurate and universal technique for mass density measurements. |
| title | Optical Measurement of Mass Density of Biological Samples |
| topic | Soft Condensed Matter |
| url | https://arxiv.org/abs/2508.07899 |