PADReg: Physics-Aware Deformable Registration Guided by Contact Force for Ultrasound Sequences

Fuente: arXiv
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Autori principali: Geng, Yimeng, Zhao, Mingyang, Xu, Fan, Cao, Guanglin, Meng, Gaofeng, Liu, Hongbin
Natura: Preprint
Pubblicazione: 2025
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author Geng, Yimeng
Zhao, Mingyang
Xu, Fan
Cao, Guanglin
Meng, Gaofeng
Liu, Hongbin
author_facet Geng, Yimeng
Zhao, Mingyang
Xu, Fan
Cao, Guanglin
Meng, Gaofeng
Liu, Hongbin
contents Ultrasound deformable registration estimates spatial transformations between pairs of deformed ultrasound images, which is crucial for capturing biomechanical properties and enhancing diagnostic accuracy in diseases such as thyroid nodules and breast cancer. However, ultrasound deformable registration remains highly challenging, especially under large deformation. The inherently low contrast, heavy noise and ambiguous tissue boundaries in ultrasound images severely hinder reliable feature extraction and correspondence matching. Existing methods often suffer from poor anatomical alignment and lack physical interpretability. To address the problem, we propose PADReg, a physics-aware deformable registration framework guided by contact force. PADReg leverages synchronized contact force measured by robotic ultrasound systems as a physical prior to constrain the registration. Specifically, instead of directly predicting deformation fields, we first construct a pixel-wise stiffness map utilizing the multi-modal information from contact force and ultrasound images. The stiffness map is then combined with force data to estimate a dense deformation field, through a lightweight physics-aware module inspired by Hooke's law. This design enables PADReg to achieve physically plausible registration with better anatomical alignment than previous methods relying solely on image similarity. Experiments on in-vivo datasets demonstrate that it attains a HD95 of 12.90, which is 21.34\% better than state-of-the-art methods. The source code is available at https://github.com/evelynskip/PADReg.
format Preprint
id arxiv_https___arxiv_org_abs_2508_08685
institution arXiv
publishDate 2025
record_format arxiv
spellingShingle PADReg: Physics-Aware Deformable Registration Guided by Contact Force for Ultrasound Sequences
Geng, Yimeng
Zhao, Mingyang
Xu, Fan
Cao, Guanglin
Meng, Gaofeng
Liu, Hongbin
Computer Vision and Pattern Recognition
Ultrasound deformable registration estimates spatial transformations between pairs of deformed ultrasound images, which is crucial for capturing biomechanical properties and enhancing diagnostic accuracy in diseases such as thyroid nodules and breast cancer. However, ultrasound deformable registration remains highly challenging, especially under large deformation. The inherently low contrast, heavy noise and ambiguous tissue boundaries in ultrasound images severely hinder reliable feature extraction and correspondence matching. Existing methods often suffer from poor anatomical alignment and lack physical interpretability. To address the problem, we propose PADReg, a physics-aware deformable registration framework guided by contact force. PADReg leverages synchronized contact force measured by robotic ultrasound systems as a physical prior to constrain the registration. Specifically, instead of directly predicting deformation fields, we first construct a pixel-wise stiffness map utilizing the multi-modal information from contact force and ultrasound images. The stiffness map is then combined with force data to estimate a dense deformation field, through a lightweight physics-aware module inspired by Hooke's law. This design enables PADReg to achieve physically plausible registration with better anatomical alignment than previous methods relying solely on image similarity. Experiments on in-vivo datasets demonstrate that it attains a HD95 of 12.90, which is 21.34\% better than state-of-the-art methods. The source code is available at https://github.com/evelynskip/PADReg.
title PADReg: Physics-Aware Deformable Registration Guided by Contact Force for Ultrasound Sequences
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2508.08685