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Détails bibliographiques
Auteurs principaux: Andersena, Jonas Valbjørn, Karlsen, Anders Peder Højer, Olsen, Markus Harboe, Pedersen, Nikolaj Krebs
Format: Preprint
Publié: 2025
Sujets:
Accès en ligne:https://arxiv.org/abs/2508.09059
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Table des matières:
  • This paper introduces the OPIAID algorithm, a novel approach for predicting and recommending personalized opioid dosages for individual patients. The algorithm optimizes pain management while minimizing opioid related adverse events (ORADE) by employing machine learning models trained on observational electronic health records (EHR) data. It leverages a causal machine learning approach to understand the relationship between opioid dose, case specific patient and intraoperative characteristics, and pain versus ORADE outcomes. The OPIAID algorithm considers patient-specific characteristics and the influence of different opiates, enabling personalized dose recommendations. This paper outlines the algorithm's methodology and architecture, and discusses key assumptions, and approaches to evaluating its performance.